Microstructured Waveguide Sensors for Point-of-Care Health Screening
Rattachement africain : ru. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Biosensor technologies in medicine, as in many other areas, are replacing labor-intensive methods of monitoring human health. This paper presents the results of experimental studies on label-free sensors based on a hollow core microstructured optical waveguide (HC-MOW) for human blood serum analysis. The MOWs with a hollow core of 247.5 µm in diameter were manufactured and used in our work. These parameters allow the hollow core to be filled with high-viscosity solutions due to the capillary properties of the fiber. Calculations of the spectral properties of the HC-MOW fiber were carried out and experimentally confirmed. Twenty-one blood serum samples from volunteers were analyzed using standard photometry (commercial kits) and an experimental biosensor. The obtained transmission spectra were processed by the principal component analysis method and conclusions were drawn about the possibility of using this biosensor in point-of-care medicine. A significant difference was shown between the blood serum of healthy patients and patients with confirmed diagnoses and a long history of cardiovascular system abnormalities. Algorithms for spectra processing using the Origin program are presented.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Microstructured Waveguide Sensors for Point-of-Care Health Screening
- Date Crossref
- 20/04/2025
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Saratov State Medical University Department of Hospital Therapy pays non établi dans la noticeUniversité ou école supérieure
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Saratov State University Institution of Physics and Science Medical Center pays non établi dans la noticeUniversité ou école supérieure
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National Research Tomsk State University Laboratory of Laser Molecular Imaging and Machine Learning pays non établi dans la noticeUniversité ou école supérieure
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Institute of Precision Mechanics and Control pays non établi dans la noticeStructure de recherche
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SPE LLC “Nanostructured Glass Technology” (SPE LLC “NGT”) pays non établi dans la noticeInstitution
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Regional Clinical Hospital Department of Cardiology pays non établi dans la noticeÉtablissement de santé
Department of Hospital Therapy — Saratov State Medical University, Institution of Physics and Science Medical Center — Saratov State University et Laboratory of Laser Molecular Imaging and Machine Learning — National Research Tomsk State University, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.