Phytochemical Analysis and Biological Activities of Wollemia nobilis W.G.Jones, K.D.Hill & J.M.Allen Leaves Collected in the Botanical Garden of Rome
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
In this work, a preliminary screening of the bioactivities of an ethanolic extract obtained from the leaves of Wollemia nobilis W.G.Jones, K.D.Hill & J.M.Allen was carried out to explore its potential pharmaceutical applications. In particular, the radical scavenging, chelating, reducing antiglycative, antimicrobial and antifungal activities as well as the inhibitory effects on the production of aflatoxin B1 in Aspergillus flavus Link were evaluated. The extract demonstrated promising biological activities, although generally with lower potency compared to the positive control. To identify the metabolites potentially responsible for these effects, the extract was subjected to phytochemical analysis evidencing the presence of eight known compounds. Among them, 15-agathic acid methyl ester (1) and ladanein (5) were reported for the first time in this species. Furthermore methyl-(E)-communate (2), 7,4′,7″,4‴-tetra-O-methyl-robustaflavone (6), agathisflavone (7) and quinic acid (8) were detected for the first time in the leaf tissue of W. nobilis. Their presence and the presence of isocupressic acid (3) and acetyl-isocupressic acid (4) in this species highlights the taxonomic correlations within the Araucariaceae family and suggests a possible contribution of these compounds in the bioactivities of the extract. However, further studies are required to confirm these contributions and to elucidate their mechanisms of action.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Phytochemical Analysis and Biological Activities of Wollemia nobilis W.G.Jones, K.D.Hill & J.M.Allen Leaves Collected in the Botanical Garden of Rome
- Date Crossref
- 19/04/2025
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Link Campus University pays non établi dans la noticeUniversité ou école supérieure
-
Sapienza University of Rome pays non établi dans la noticeUniversité ou école supérieure
-
Dipartimento di Scienze della Vita pays non établi dans la noticeInstitution
-
Dipartimento di Biologia Ambientale pays non établi dans la noticeInstitution
-
Dipartimento di Chimica pays non établi dans la noticeInstitution
-
NMR-Based Metabolomics Laboratory (NMLab) pays non établi dans la noticeStructure de recherche
-
Dipartimento di Fisiologia e Farmacologia “V. Erspamer” pays non établi dans la noticeInstitution
Link Campus University, Sapienza University of Rome et Dipartimento di Scienze della Vita, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.