Revisiting maternal age and child health: A nationwide birth cohort study in Taiwan
Rattachement africain : tw, kr. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Delayed childbearing is a growing trend globally, with Taiwan experiencing one of the steepest increases in maternal age. Advanced maternal age affects offspring health, including birth outcomes and long-term morbidity. However, its impact in Taiwan remains underexplored. This study investigates these effects using a nationwide birth cohort. METHODS: This retrospective cohort study utilized data from Taiwan's National Health Insurance Research Database (NHIRD), covering infants born from January 1, 2004, to December 31, 2014. The cohort included 2,068,672 infants, categorized into six maternal age groups: <20, 20-24, 25-29, 30-34, 35-40, and ≥40 years. Principal outcomes were stillbirth, mortality, preterm birth, congenital anomalies, neurodevelopmental outcomes, and atopic diseases. Multivariate logistic regression models adjusted for covariates to assess associations between maternal age and health outcomes. RESULTS: Among the 2,068,672 infants, stillbirth and mortality rates were highest in infants born to mothers <20 years, decreased with increasing maternal age, then rose again for mothers ≥30 years, showing a reverse J-shaped pattern. Similar trends were noted for preterm birth, congenital anomalies, and neurodevelopmental outcomes. Atopic diseases followed a nonlinear trend, peaking at maternal age 25-34 years. CONCLUSION: Maternal age significantly impacts child health, with risks associated with both younger and older maternal ages. These findings are crucial for regions experiencing delayed childbearing. Further research is needed to explore underlying mechanisms and establish causality.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Revisiting maternal age and child health: A nationwide birth cohort study in Taiwan
- Date Crossref
- 01/07/2026
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Taipei Medical University Hospital Department of Pediatrics pays non établi dans la noticeÉtablissement de santé
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National Taiwan University Hospital Institute of Environmental and Occupational Health Sciences pays non établi dans la noticeÉtablissement de santé
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National Taiwan University Institute of Epidemiology and Preventive Medicine pays non établi dans la noticeUniversité ou école supérieure
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National Health Research Institutes pays non établi dans la noticeOrganisation à but non lucratif
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National Taipei University of Nursing and Health Science pays non établi dans la noticeUniversité ou école supérieure
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Cathay General Hospital pays non établi dans la noticeÉtablissement de santé
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Ministry of Health and Welfare pays non établi dans la noticeOrganisme public
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Ming Chuan University Department of Pediatrics pays non établi dans la noticeUniversité ou école supérieure
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Taipei Medical University pays non établi dans la noticeUniversité ou école supérieure
Department of Pediatrics — Taipei Medical University Hospital, Institute of Environmental and Occupational Health Sciences — National Taiwan University Hospital et Institute of Epidemiology and Preventive Medicine — National Taiwan University, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.