Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with twin pregnancy: meta-analysis of individual participant data
Rattachement africain : au, de, Égypte, br, us, es, it, ca, at, gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Objective: To quantify the prognostic value of mid-trimester cervical length for spontaneous preterm birth in asymptomatic women with twin pregnancy and to assess whether other factors may modify any association. Designs: A two stage meta-analysis of individual participant data in a Cox proportional hazard model was performed using cervical length as a continuous variable. Data sources: Medline, Embase, Cochrane, and LILACS, among others, were searched to identify eligible studies; the search was from 1 January 2000 to 30 September 2020. Risk of bias was assessed with the QUIPS tool. Studies were from eight countries between 2001 and 2018. Eligibility criteria: Individual participant data were sought for eligible studies that reported mid-trimester (defined between 16 and 26 weeks) transvaginal sonographic cervical length and also gestational age at birth in asymptomatic women with twin pregnancy. The primary outcome was spontaneous preterm birth before 37 weeks. Results: Among 29 eligible studies, authors of 17 studies provided individual participant data for 6437 women with a twin pregnancy (69.1% of individual participant data). Mean cervical length measurement was 39 mm (SD=9, range 1-74 mm). 2889 women (44.9%) delivered before 37 weeks' gestation, and 934 (14.9%) delivered before 34 weeks. Each 1 mm increase in cervical length was associated with a 4.0% reduction in the rate of spontaneous preterm birth before 37 weeks (hazard ratio 0.96 (95% confidence interval 0.95 to 0.97)), and a 6.8% reduction in the rate of spontaneous preterm birth before 34 weeks' gestation (0.93 (0.92 to 0.95)). The prognostic value remained stable in models adjusting for different sets of variables. Conclusion: The prognostic value of cervical length for spontaneous preterm birth in twin pregnancy is on a continuous scale. No specific cervical length has been identified that can reliably predict or exclude all spontaneous preterm births. Study registration: CRD42020146987.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with twin pregnancy: meta-analysis of individual participant data
- Date Crossref
- 01/04/2025
- Éditeur
- BMJ
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Monash University Department of Obstetrics and Gynaecology pays non établi dans la noticeUniversité ou école supérieure
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The University of Sydney NHMRC Clinical Trial Centre pays non établi dans la noticeUniversité ou école supérieure
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National Health and Medical Research Council pays non établi dans la noticeOrganisme public
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University of Rostock pays non établi dans la noticeUniversité ou école supérieure
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Cairo University Department of Obstetrics and Gynaecology Cairo University, Égypte (code pays fourni par la source)Université ou école supérieure
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Universidade de São Paulo Faculdade de Medicina pays non établi dans la noticeUniversité ou école supérieure
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VA Midwest Health Care Network pays non établi dans la noticeÉtablissement de santé
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Children's Minnesota pays non établi dans la noticeÉtablissement de santé
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Midwest Orthopaedic Research Foundation pays non établi dans la noticeOrganisation à but non lucratif
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Hospital Universitario Miguel Servet pays non établi dans la noticeÉtablissement de santé
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Icahn School of Medicine at Mount Sinai Department of Obstetrics pays non établi dans la noticeUniversité ou école supérieure
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University of California San Diego Departments of Obstetrics pays non établi dans la noticeUniversité ou école supérieure
Department of Obstetrics and Gynaecology — Monash University, NHMRC Clinical Trial Centre — The University of Sydney et National Health and Medical Research Council, avec 9 autres affiliations. Pays d’affiliation : Égypte.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.