Optimizing stress ulcer prophylaxis practices and reducing associated costs in intensive care units: a non-randomized controlled study
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Le résumé fourni par la source
Objective: This study evaluated the use of stress ulcer prophylaxis (SUP), assessed the costs associated with inappropriate use, and highlighted the impact of clinical pharmacists on improving adherence to the SUP guidelines. Method: A prospective, non-randomized controlled study was carried out in two intensive care units (ICUs) of a training and research hospital between 1 June 2023 and 1 December 2023. Routine care services were provided for the observation group (OG) patients. In the guideline group (GG) patients, SUP management and routine care were performed according to ASHP guidelines. The physician and clinical pharmacist jointly evaluated the patients to determine the suitability of their SUP indications. Adherence rates to ASHP guidelines and the costs associated with nonadherence were evaluated. Results: A total of 196 patients were included in the study: 121 in the OG and 75 in the GG. A total of 54.6% of the patients were male, and the reason for hospitalization was mainly surgery (52.6%). SUP use was higher in OG (100%) than in GG (42.6%) (p < 0.001). The indication rate according to the ASHP guidelines was significantly higher in the GG group (100%) than in the OG group (54.5%) (p < 0.001). Dosage form adherence was significantly lower in the OG (0%) than in the GG (100%) (p < 0.001). The costs associated with proton pump inhibitor use for inappropriate indications and incorrect dosage forms were $60 versus $0 (p < 0.001) and $321 versus $0 (p < 0.001) in OG and GG, respectively. Overall, cost savings of $327 were achieved in the GG group. Conclusion: Inappropriate SUP use is common in the ICUs. Adequate adherence to guidelines and proactive involvement of clinical pharmacists may reduce inappropriate SUP in ICUs and the associated costs.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Optimizing stress ulcer prophylaxis practices and reducing associated costs in intensive care units: a non-randomized controlled study
- Date Crossref
- 10/04/2025
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi pays non établi dans la noticeÉtablissement de santé
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Education Training And Research pays non établi dans la noticeOrganisation à but non lucratif
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Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi pays non établi dans la noticeÉtablissement de santé
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Türkisch-Deutsche Universität pays non établi dans la noticeUniversité ou école supérieure
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Prof. Dr. Cemil Taşcıoğlu City Hospital pays non établi dans la noticeÉtablissement de santé
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Gaziosmanpaşa Education and Research Hospital pays non établi dans la noticeÉtablissement de santé
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Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital pays non établi dans la noticeÉtablissement de santé
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Altınbaş University pays non établi dans la noticeUniversité ou école supérieure
Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi, Education Training And Research et Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.