Challenges of lithium prescription in bipolar disorders in Nigeria
Rattachement africain : Nigéria. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Lithium prescription rates have witnessed a significant downward trend over the years in different continents despite evidence of its clinical efficacy in the acute and long-term maintenance treatment of Bipolar Disorder (BD). Nigeria has a paucity of data on lithium use in BD management. Hence, we aim to investigate the lithium prescription rate and factors influencing its use among Nigerian psychiatrists and trainee psychiatrists. METHODS: A cross-sectional survey involving 203 respondents working in different accredited psychiatric training facilities in Nigeria was conducted between April and May 2024 using a predesigned online Google form. Information relating to lithium use in managing the different phases of BD and factors influencing its use were assessed. RESULTS: The mean age of the respondents was 37.98 (± 6.85) years. The lithium prescription rate is low (10.89%). There is a significant association between the respondents' awareness of clinical practice guidelines (CPG) and good adherence to CPG (p = 0.003), but this did not significantly influence lithium prescription among them. Older years of practice influence prescribing lithium (p = < 0.001). Monitoring and availability of lithium constituted significant concerns for lithium use, among other factors (p = 0.032). CONCLUSION: The study revealed a low lithium prescription rate among Nigerian psychiatrists and trainee psychiatrists compared to international studies. There is a need for concerted efforts towards addressing the identified factors. A review of the existing local CPG in line with the best evidence is warranted for improved clinical outcomes. ETHICS REGISTRATION: The study was approved by the Hospital Research and Ethical Committee (HREC) of the University of Port Harcourt Teaching Hospital (UPTH) with approval protocol number (UPTH/ADM/90/S.11/VOL.XI/1688). CLINICAL TRIAL NUMBER: Not applicable.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Challenges of lithium prescription in bipolar disorders in Nigeria
- Date Crossref
- 31/03/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Port Harcourt Department of Mental Health University of Port Harcourt, Nigéria (code pays fourni par la source)Université ou école supérieure
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Kwara State Polytechnic Nigéria (code pays fourni par la source)Université ou école supérieure
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Kwara State University Department of Behavioural Sciences Ilorin, Nigéria (code pays fourni par la source)Université ou école supérieure
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Federal Neuro Psychiatric Hospital Nigéria (code pays fourni par la source)Établissement de santé
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Ekiti State University Department of Psychiatry Ado-Ekiti, Nigéria (code pays fourni par la source)Université ou école supérieure
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University of Maiduguri Department of Psychiatry University of Maiduguri, Nigéria (code pays fourni par la source)Université ou école supérieure
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Department of Clinical Services Kaduna State, Nigéria (pays nommé en fin d’affiliation)Établissement de santé
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Federal Neuropsychiatric Hospital Department of Medical Services Maiduguri, Nigéria (pays nommé en fin d’affiliation)Établissement de santé
Department of Mental Health — University of Port Harcourt (University of Port Harcourt, Nigéria), Kwara State Polytechnic (Nigéria) et Department of Behavioural Sciences — Kwara State University (Ilorin, Nigéria), avec 5 autres affiliations. Pays d’affiliation : Nigéria.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.