Incidence of loss to follow-up and associated factors among mothers on antiretroviral therapy in the context of elimination of mother-to-child transmission of HIV in two health districts of Bobo-Dioulasso in Burkina Faso

Résumé fourni par la source

INTRODUCTION: Since 2017, Burkina Faso has rolled out a plan to eliminate vertical transmission of HIV (eMTCT). Elimination will only be achieved when mothers have regular follow-up and good compliance with antiretroviral therapy (ART). The aim of this article is to study the incidence and associated factors for loss to follow-up (LTFU ), in women living with HIV (WLHIV) monitored as part of the eMTCT. METHODS: This study consisted of a retrospective analysis of routinely collected data from pregnant women who were screened and initiated ART in the Do and Dafra health districts of Bobo-Dioulasso between 2017 and 2020 as part of the eMTCT. The study ran from May 2023 to March 2024. The Kaplan-Meier model was used to estimate the rate of LTFU; the Cox model was used for identification of factors associated with LTFU and verification of Kaplan-Meier results. RESULTS: Three hundred and four newly diagnosed pregnant WLHIV were included in this study. The median age of the mothers was 30 [24; 36] years. The incidence of LTFU was 22.9 per 100 person-years. Younger age (HR = 2.40; 95%CI: 1.37-4.20) was associated with a higher incidence of LTFU, whereas urban residence (HR = 0.57; 95%CI: 0.39-0.85), in contrast to rural residence, was associated with a lower incidence of LTFU. CONCLUSION: The study showed a high incidence of LTFU, associated with younger age and rural residence, in the eMTCT programme in Burkina Faso.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.