A nomogram based on systemic inflammation response index and clinical risk factors for prediction of short-term prognosis of very elderly patients with hypertensive intracerebral hemorrhage
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Le résumé fourni par la source
Objective To develop and validate a nomogram based on systemic inflammation response index (SIRI) and clinical risk factors to predict short-term prognosis in very elderly patients with hypertensive intracerebral hemorrhage (HICH). Methods A total of 324 very elderly HICH patients from January 2017 to June 2024 were retrospectively enrolled and randomly divided into two cohorts for training ( n = 227) and validation ( n = 97) according to the ratio of 7:3. Independent predictors of poor prognosis were analyzed using univariate and multivariate logistic regression analyses. Furthermore, a nomogram prediction model was built. The area under the receiver operating characteristic curves (AUC), calibration plots and decision curve analysis (DCA) were used to evaluate the performance of the nomogram in predicting the prognosis of very elderly HICH. Results By univariate and stepwise multivariate logistic regression analyses, GCS score ( p < 0.001), hematoma expansion ( p = 0.049), chronic obstructive pulmonary disease ( p = 0.010), and SIRI ( p = 0.005) were independent predictors for the prognosis in very elderly patients with HICH. The nomogram showed the highest predictive efficiency in the training cohort (AUC = 0.940, 95% CI: 0.909 to 0.971) and the validation cohort (AUC = 0.884, 95% CI: 0.813 to 0.954). The calibration curve indicated that the nomogram had good calibration. DCA showed that the nomogram had high applicability in clinical practice. Conclusion The nomogram incorporated with the SIRI and clinical risk factors has good potential in predicting the short-term prognosis of very elderly HICH.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A nomogram based on systemic inflammation response index and clinical risk factors for prediction of short-term prognosis of very elderly patients with hypertensive intracerebral hemorrhage
- Date Crossref
- 28/03/2025
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Chinese People's Armed Police Force pays non établi dans la noticeOrganisme public
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Lanzhou University pays non établi dans la noticeUniversité ou école supérieure
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Shenyang Fifth People Hospital pays non établi dans la noticeÉtablissement de santé
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The First School of Clinical Medical pays non établi dans la noticeUniversité ou école supérieure
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Tianjin Key Laboratory of Neurotrauma Repair pays non établi dans la noticeStructure de recherche
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Fuyang Fifth People's Hospital Department of Neurosurgery pays non établi dans la noticeÉtablissement de santé
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Linquan County People's Hospital Department of Neurosurgery pays non établi dans la noticeÉtablissement de santé
Chinese People's Armed Police Force, Lanzhou University et Shenyang Fifth People Hospital, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.