Gut Microbiome in Pulmonary Arterial Hypertension – An Emerging Frontier

Le résumé fourni par la source

Pulmonary arterial hypertension is characterized by vascular and systemic inflammation. The gut microbiome influences the host immune system. Here we review the emerging preclinical and clinical evidence that strongly suggest that alterations in the gut microbiome may either initiate or facilitate progression of established pulmonary arterial hypertension by modifying systemic immune responses. We also briefly describe studies delineating the contributions of infections to pulmonary arterial hypertension pathogenesis.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.