Factors associated with diagnostic and treatment intervals in colorectal cancer: A linked data study
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Le résumé fourni par la source
This research aimed to assess the length of intervals before diagnosis and treatment for colorectal cancer in Australia using linked datasets, and to determine any factors associated with interval length. A colorectal cancer clinical registry was linked to general practice electronic medical record data and routinely collected hospital referral datasets to determine the length of four key intervals in the time before first treatment. Cox proportional hazards regression was used to assess associations between individual characteristics (sociodemographic variables such as age and sex, and disease characteristics such as cancer subtype and treatment approach) and the length of each interval. Sample sizes available for analysis varied by interval, ranging from 99 to 9359. The median interval length ranged from 21 (IQR 5-38) days for the time between diagnosis and treatment to 63 (IQR 24-218) days for the time between first presentation and diagnosis. Overall, few measured characteristics were associated with the lengths of any of the intervals. Of note, shorter diagnostic intervals were associated with presenting to the general practitioner with alarm symptoms, and people proceeding to surgery as initial treatment had shorter times to treatment than any other treatment modality. Given disease and medical system factors were associated with interval length, broad improvements to the overall efficient functioning of the healthcare system are likely to improve timeliness. More targeted interventions could focus on processes at the transitions between different levels of the healthcare system and implementing recommended maximum lengths of intervals along the diagnostic and treatment pathway.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Factors associated with diagnostic and treatment intervals in colorectal cancer: A linked data study
- Date Crossref
- 13/03/2025
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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The University of Melbourne Department of General Practice and Centre for Cancer Research pays non établi dans la noticeUniversité ou école supérieure
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Walter and Eliza Hall Institute of Medical Research pays non établi dans la noticeOrganisation à but non lucratif
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Western Health pays non établi dans la noticeÉtablissement de santé
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Primary Care Collaborative Clinical Trials Group pays non établi dans la noticeInstitution
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Melbourne School of Population and Global Health pays non établi dans la noticeUniversité ou école supérieure
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Victorian Cancer Registry Melbourne Australia pays non établi dans la noticeInstitution
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Department of Surgery University of Melbourne Parkville Australia pays non établi dans la noticeUniversité ou école supérieure
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Primary Care Collaborative Cancer Clinical Trials Group (PC4) Carlton Australia pays non établi dans la noticeÉtablissement de santé
Department of General Practice and Centre for Cancer Research — The University of Melbourne, Walter and Eliza Hall Institute of Medical Research et Western Health, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.