Dynamic regulation of cortical interneuron wiring

Résumé fourni par la source

Inhibitory interneurons play crucial roles in modulating the circuits and activity patterns of the cerebral cortex. In particular, interneurons must adapt to changes in cortical activity and environmental information to drive appropriate responses. In this review, we focus on the latest progress in our understanding of the processes that regulate interneuron wiring adaptability. We discuss newly identified types of regulatory processes, from structural synaptic changes to long-range neuromodulation, and provide an update on the activity-dependent molecular underpinnings at the transcriptional and post-transcriptional levels.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.