The association between aortic and intracranial aneurysms: A systematic review

Le résumé fourni par la source

Aneurysms at different arterial sites share similar pathophysiologic and biomechanical properties. Theoretically, an association between intracranial aneurysms and aortic aneurysms could exist as well, which might be important for screening purposes. This systematic review aims to evaluate the potential association between intracranial and aortic aneurysms. A systematic search was performed to identify studies that investigated the occurrence of intracranial aneurysms in patients with aortic aneurysms (sub-question A) or vice versa (sub-question B). Methodological quality was assessed by using a modified version of the Newcastle-Ottawa Scale. In total, 12 studies were included in this systematic review. For sub-question A, an occurrence rate of 5% to 12% was identified for aortic aneurysms in patients with intracranial aneurysms. An occurrence rate of 5% to 22% for intracranial aneurysms was found in patients with an aortic aneurysm (sub-question B). This systematic review suggests a potential association between intracranial and aortic aneurysms, as higher occurrences compared with the general population or controls were found. Unfortunately, very little research has been performed about the subject and because of this, a definite conclusion could not be made. Screening for aortic aneurysms in patients with intracranial aneurysms might be valuable for timely diagnosis, follow-up, treatment, and potentially be cost-effective. Screening vice versa is unclear; important factors that remain unclear include the costs and the uncertain survival benefit of detecting intracranial aneurysms in patients with an aortic aneurysm. To make a more reliable statement about this, more high-quality research must follow.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.