Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia
Rattachement africain : in, tr, cn, hk, dk, pk, es, it, gb, th, us, jp, fr, lb, kr, tw, de, ca, id, ph, bd, Égypte, mx, sg, am, au, cl, mm, lk, mn, my, np, kz. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Acute-on-chronic liver failure (ACLF) is a condition associated with high mortality in the absence of liver transplantation. There have been various definitions proposed worldwide. The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set in 2004 on ACLF was published in 2009, and the "APASL ACLF Research Consortium (AARC)" was formed in 2012. The AARC database has prospectively collected nearly 10,500 cases of ACLF from various countries in the Asia-Pacific region. This database has been instrumental in developing the AARC score and grade of ACLF, the concept of the 'Golden Therapeutic Window', the 'transplant window', and plasmapheresis as a treatment modality. Also, the data has been key to identifying pediatric ACLF. The European Association for the Study of Liver-Chronic Liver Failure (EASL CLIF) and the North American Association for the Study of the End Stage Liver Disease (NACSELD) from the West added the concepts of organ failure and infection as precipitants for the development of ACLF and CLIF-Sequential Organ Failure Assessment (SOFA) and NACSELD scores for prognostication. The Chinese Group on the Study of Severe Hepatitis B (COSSH) added COSSH-ACLF criteria to manage hepatitis b virus-ACLF with and without cirrhosis. The literature supports these definitions to be equally effective in their respective cohorts in identifying patients with high mortality. To overcome the differences and to develop a global consensus, APASL took the initiative and invited the global stakeholders, including opinion leaders from Asia, EASL and AASLD, and other researchers in the field of ACLF to identify the key issues and develop an evidence-based consensus document. The consensus document was presented in a hybrid format at the APASL annual meeting in Kyoto in March 2024. The 'Kyoto APASL Consensus' presented below carries the final recommendations along with the relevant background information and areas requiring future studies.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia
- Date Crossref
- 01/02/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Institute of Liver and Biliary Sciences Department of Hepatology pays non établi dans la noticeÉtablissement de santé
-
Asian Institute of Gastroenterology pays non établi dans la noticeÉtablissement de santé
-
Medanta The Medicity pays non établi dans la noticeÉtablissement de santé
-
Ankara University pays non établi dans la noticeUniversité ou école supérieure
-
Institute of Post Graduate Medical Education and Research pays non établi dans la noticeUniversité ou école supérieure
-
Lakeshore Hospital pays non établi dans la noticeÉtablissement de santé
-
Post Graduate Institute of Medical Education and Research pays non établi dans la noticeUniversité ou école supérieure
-
Sir Ganga Ram Hospital pays non établi dans la noticeÉtablissement de santé
-
Govind Ballabh Pant Hospital pays non établi dans la noticeÉtablissement de santé
-
Sanjay Gandhi Post Graduate Institute of Medical Sciences pays non établi dans la noticeStructure de recherche
-
King George's Medical University pays non établi dans la noticeUniversité ou école supérieure
-
Dayanand Medical College & Hospital pays non établi dans la noticeUniversité ou école supérieure
Department of Hepatology — Institute of Liver and Biliary Sciences, Asian Institute of Gastroenterology et Medanta The Medicity, avec 9 autres affiliations. Pays d’affiliation : Égypte.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.