The impact of antibiotic therapy in psoriasis patients with active streptococcal infection: A prospective study
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
The association between psoriasis and streptococcal infection has been widely explored in both children and adults. However, the exact impact of Streptococcus pharyngeal infection on the course of psoriasis is not fully comprehended. This study explored the impact of Streptococcus pharyngeal infection on psoriasis and investigated the effectiveness of systemic antibiotic therapy in conjunction with standard topical treatment for psoriatic patients with concomitant streptococcal throat infection. The research involved 115 patients with mild-to-moderate psoriasis, clinically assessed using the Psoriasis Area and Severity Index (PASI). Patients with active streptococcal infection were administered adjunctive systemic antibiotic therapy along with standard local treatment for psoriasis, while psoriasis patients without evidence of infection received the local topical treatment only. Streptococcal infections were more common in psoriasis patients compared to healthy controls. A group of psoriasis patients with active streptococcal throat infections, treated with antibiotics in addition to standard topical psoriasis therapy, did not show any difference in PASI score reduction compared to those without evidence of active infection. While our study did not show a statistically significant reduction in PASI scores in psoriasis patients with streptococcal throat infections treated with antibiotics, it highlights the complex interaction between infection and psoriasis. Larger studies with longer follow-up may better clarify this relationship, contributing to stronger evidence for or against the use of antibiotics in managing psoriasis triggered by streptococcal infections.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The impact of antibiotic therapy in psoriasis patients with active streptococcal infection: A prospective study
- Date Crossref
- 03/02/2025
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Florence Section of Dermatology pays non établi dans la noticeUniversité ou école supérieure
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Azienda Ospedaliero-Universitaria Careggi pays non établi dans la noticeÉtablissement de santé
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Istituto di Fisiologia Clinica pays non établi dans la noticeStructure de recherche
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National Research Council pays non établi dans la noticeOrganisation à but non lucratif
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Azienda Usl Toscana Centro pays non établi dans la noticeÉtablissement de santé
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Microbiology and Virology Unit Careggi University Hospital Florence Italy Microbiology and Virology Unit pays non établi dans la noticeUniversité ou école supérieure
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Infectious and Tropical Diseases Unit Azienda Ospedaliero‐Universitaria Careggi Florence Italy pays non établi dans la noticeInstitution
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Institute of Clinical Physiology pays non établi dans la noticeStructure de recherche
Section of Dermatology — University of Florence, Azienda Ospedaliero-Universitaria Careggi et Istituto di Fisiologia Clinica, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.