Robotic-assisted versus conventional total knee arthroplasty: a systematic review and meta-analysis of alignment accuracy and clinical outcomes

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Background: Robotic-assisted total knee arthroplasty (RA-TKA) has emerged as an alternative to conventional TKA (C-TKA), aiming to improve surgical precision and patient outcomes. This systematic review and meta-analysis study compares the efficacy of RA-TKA versus C-TKA. Methods: A comprehensive search of five databases (PubMed, EMBASE, Web of Science, SCOPUS, and Cochrane Library) was conducted. We included all published randomized controlled trials (RCTs) from inception to August 2024. Meta-analysis was done using RevMan 5.4 package. Results: Twenty-one RCTs involving 2692 patients were involved. RA-TKA demonstrated significantly lower mechanical alignment outlier rates (risk ratio = 0.33, 95% confidence interval (CI)[0.19, 0.59], P = 0.0002) and less deviation from neutral mechanical axis (mean difference, MD = −0.93° [−1.20, −0.66], P < 0.00001) compared to C-TKA. No significant differences were found in WOMAC or Oxford Knee Scores at various follow-up points. RA-TKA was associated with longer operative times (MD = 19.94 minutes [9.2, 30.68], P = 0.0003) but showed no significant difference in intraoperative blood loss. Postoperative Knee Society Scores were slightly higher in the RA-TKA group (MD = 1.03 [0.50, 1.57], P = 0.0002). Conclusion: RA-TKA offers improved mechanical alignment accuracy compared to C-TKA but does not demonstrate superior short to medium-term functional outcomes. The technology is associated with longer operative times. These findings suggest that while RA-TKA may enhance surgical precision, its clinical benefits and cost-effectiveness require further evaluation, particularly in long-term studies.

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