The B Chromosome of Pseudococcus viburni: A Selfish Chromosome that Exploits Whole-Genome Meiotic Drive
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Le résumé fourni par la source
Meiosis is generally a fair process: each chromosome has a 50% chance of being included into each gamete. However, meiosis can become aberrant with some chromosomes having a higher chance of making it into gametes than others. Yet, why and how such systems evolve remains unclear. Here, we study the unusual reproductive genetics of mealybugs, where only maternal-origin chromosomes are included in gametes during male meiosis, while paternal chromosomes are eliminated. One species-Pseudococcus viburni-has a segregating B chromosome that drives by escaping paternal genome elimination. We present whole genome and gene expression data from lines with and without B chromosomes. We identify B-linked sequences including 204 protein-coding genes and a satellite repeat that makes up a significant proportion of the chromosome. The few paralogs between the B and the core genome are distributed throughout the genome, arguing against a simple, or at least recent, chromosomal duplication of one of the autosomes to create the B. We do, however, find one 373 kb region containing 146 genes that appears to be a recent translocation. Finally, we show that while many B-linked genes are expressed during meiosis, most of these are encoded on the recently translocated region. Only a small number of B-exclusive genes are expressed during meiosis. Of these, only one was overexpressed during male meiosis, which is when the drive occurs: an acetyltransferase involved in H3K56Ac, which has a putative role in meiosis and is, therefore, a promising candidate for further studies.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- The B Chromosome of <i>Pseudococcus viburni:</i> A Selfish Chromosome that Exploits Whole-Genome Meiotic Drive
- Date Crossref
- 01/01/2025
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Illinois Chicago pays non établi dans la noticeUniversité ou école supérieure
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University of Edinburgh pays non établi dans la noticeUniversité ou école supérieure
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Wellcome Sanger Institute Tree of Life Programme pays non établi dans la noticeOrganisation à but non lucratif
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University of Florida Department of Entomology and Nematology pays non établi dans la noticeUniversité ou école supérieure
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University of East Anglia pays non établi dans la noticeUniversité ou école supérieure
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Uppsala University Department of Organismal Biology pays non établi dans la noticeUniversité ou école supérieure
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University of Illinois at Chicago Department of Biological Sciences pays non établi dans la noticeUniversité ou école supérieure
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School of Biological Sciences pays non établi dans la noticeUniversité ou école supérieure
University of Illinois Chicago, University of Edinburgh et Tree of Life Programme — Wellcome Sanger Institute, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.