Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds
Rattachement africain : pk, sa, cn. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Pesticides, including fipronil, are used mainly in agriculture; however, in veterinary and animal husbandry, their potential use is to control the pests responsible for vector-borne diseases. Their residues in agriculture products and direct use on farms are responsible for potentially harming livestock and poultry. So, this study was designed to evaluate the toxico-pathological effects of fipronil on the immune system of poultry birds. One hundred a-day-old chicks were purchased from a local hatchery, and standard housing conditions were provided from brooding till the end of the trail. The temperature at brooding was kept at 33°C; later on, it was maintained at 26-28°C, and the humidity was at 60-70%. Clean water and a basal diet were provided ad libitum. After three days of acclimatization, birds were divided into five experimental groups (A to E), each containing 20 birds. Group A was kept as a control group. Fipronil was administered orally through crop tubing @ 1.5, 2.5, 3.5, and 4.5 mg/kg to groups B-E, respectively. Birds were euthanized humanely on the 15th, 30th, and 45th days of the experiment. Immunological parameters were evaluated, i.e., antibody titers against NDV and SRBCs, phagocytic activity to clear carbon particles, avian incompetence to avian tuberculin, and histopathological alterations in the lymphoid organs. The SAS® University Edition software was used for data analysis. The results indicated decreased antibody titers against NDV in the treatment groups compared to the control. Similarly, antibody response to SRBCs, phagocytic activity in clearing the carbon particles, and sensitivity to avian tuberculin in the treatment groups were also decreased. Results also revealed that the bursa of Fabricius thymus and spleen were also affected due to the toxic effect of fipronil, even at sub-lethal doses.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds
- Date Crossref
- 28/01/2025
- Éditeur
- Public Library of Science (PLoS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Agriculture Faisalabad pays non établi dans la noticeUniversité ou école supérieure
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Baqai Medical University Pathology Department pays non établi dans la noticeUniversité ou école supérieure
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King Saud University pays non établi dans la noticeUniversité ou école supérieure
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Islamia University of Bahawalpur pays non établi dans la noticeUniversité ou école supérieure
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Weifang University of Science and Technology pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Veterinary Science Department of Pathology pays non établi dans la noticeUniversité ou école supérieure
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College of Science Department of Biochemistry pays non établi dans la noticeUniversité ou école supérieure
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University College of Veterinary and Animal Sciences Department of Pathology pays non établi dans la noticeUniversité ou école supérieure
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Shandong Vocational Animal Science and Veterinary College pays non établi dans la noticeUniversité ou école supérieure
University of Agriculture Faisalabad, Pathology Department — Baqai Medical University et King Saud University, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.