Long-term Clinical Outcomes and Optimal Treatment Approaches of Degenerative Cervical Spondylosis
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Le résumé fourni par la source
STUDY DESIGN/SETTING: A retrospective cohort study. OBJECTIVE: To compare long-term outcomes and complications of cervical disc replacement (CDR) and anterior cervical discectomy and fusion (ACDF) with cage-plate constructs (CPC) and stand-alone (SA) cages in treating degenerative cervical spondylosis. SUMMARY OF BACKGROUND DATA: ACDF is commonly used for cervical radiculopathy but may increase adjacent segment degeneration (ASD). CDR has gained popularity by preserving motion and potentially reducing ASD, whereas SA cages offer a simpler alternative to CPC. Despite widespread adoption, further research is needed to clarify the long-term outcomes and associated complications. METHODS: A retrospective analysis was conducted on 1146 patients who underwent cervical surgery between 2009 and 2012 at three Chinese hospitals, grouped into CDR (n=220), CPC-ACDF (n=540), and SA-ACDF (n=386). Primary outcomes included overall success rate and complications. Secondary measures were JOA, VAS, SF-36 scores, and imaging parameters. RESULTS: The CDR group exhibited a significantly higher overall success rate compared with CPC-ACDF and SA-ACDF groups. Dysphagia incidence immediately post-surgery was significantly lower in the CDR and SA-ACDF groups compared with CPC-ACDF. At the final follow-up, implant subsidence was lowest in the CDR group. Radiographic-ASD incidence was significantly lower in the CDR and SA-ACDF groups compared with CPC-ACDF, with SA-ACDF having the lowest rate of symptomatic-ASD. The reoperation occurred in 38 (7.0%) CPC-ACDF, 18 (4.7%) SA-ACDF, and 8 (3.6%) CDR patients. Despite a 65.5% incidence of heterotopic ossification (HO), CDR partially preserved the angular range of motion. Multivariate logistic regression analysis suggested that SA-ACDF and CDR were protective factors against postoperative radiographic-ASD. Conditional nomograms demonstrated good predictive performance for symptomatic-ASD, supported by receiver operating characteristics and calibration curves. CONCLUSION: This study suggests that CDR provides similar clinical outcomes with fewer complications compared with ACDF. However, further research is needed to confirm these findings, particularly considering the variability between different CDR devices and the potential for selection bias.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Long-term Clinical Outcomes and Optimal Treatment Approaches of Degenerative Cervical Spondylosis
- Date Crossref
- 21/01/2025
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Xijing Hospital pays non établi dans la noticeÉtablissement de santé
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Air Force Medical University Department of Orthopaedics pays non établi dans la noticeUniversité ou école supérieure
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Capital Medical University Department of Spine Surgery pays non établi dans la noticeUniversité ou école supérieure
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Beijing Shijitan Hospital pays non établi dans la noticeÉtablissement de santé
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Seventh People's Hospital of Shanghai pays non établi dans la noticeÉtablissement de santé
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Shenyang The Fourth Hospital of People pays non établi dans la noticeÉtablissement de santé
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The Military General Hospital of Beijing PLA Department of Orthopaedics pays non établi dans la noticeÉtablissement de santé
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Air Force General Hospital PLA pays non établi dans la noticeÉtablissement de santé
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The Seventh People’s Hospital of Shenyang pays non établi dans la noticeÉtablissement de santé
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Air Force Medical Center Department of Orthopedics pays non établi dans la noticeÉtablissement de santé
Xijing Hospital, Department of Orthopaedics — Air Force Medical University et Department of Spine Surgery — Capital Medical University, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.