Trends in Sudden Cardiac Death Among Adults Aged 25 to 44 Years in the United States: An Analysis of 2 Large US Databases
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Le résumé fourni par la source
BACKGROUND: Sudden cardiac death (SCD) in early adults aged 25 to 44 years represents an important and unexpected cause of death. We assessed trends in SCD-related mortality in the United States from 1999 to 2020 among early adults to determine differences by sex, ethnoracial groups, urbanization, and census region. METHODS AND RESULTS: Mortality data were retrieved from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) data set from 1999 to 2020. Age-adjusted mortality rates were assessed using the Joinpoint regression modeling and expressed as estimated average annual percentage change with relative 95% CIs. Trends in prevalence of coronary artery disease/myocardial infarction, heart failure, and stroke, which may have contributed to SCD-related mortality over the same period, were obtained from the National Health and Nutrition Examination Survey. From 1999 to 2020, 10 516 US early adults aged 25 to 44 years had SCD (7832 men and 2684 women), resulting in 3.72 deaths per 1000 population, or a mean of 478 deaths annually. The relative age-adjusted mortality rate increased linearly (average annual percentage change: +1.0% [95% CI, 0.3-1.8]), without sex differences. The age-adjusted mortality rate increase was more pronounced in Black patients, Hispanic/Latinx patients, and residents of rural areas. Higher absolute numbers of SCDs were clustered in the South (47.6%). During the same period, the prevalence of coronary artery disease/myocardial infarction, heart failure, and stroke plateaued. SCD-related mortality associated with opioids/stimulants overdose significantly increased over the entire study period. CONCLUSIONS: SCD-related mortality among early adults has increased over the last 2 decades in the United States with notable racial and regional disparities.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Trends in Sudden Cardiac Death Among Adults Aged 25 to 44 Years in the United States: An Analysis of 2 Large US Databases
- Date Crossref
- 07/01/2025
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Padua pays non établi dans la noticeUniversité ou école supérieure
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University of Ferrara pays non établi dans la noticeUniversité ou école supérieure
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St David's Medical Center pays non établi dans la noticeÉtablissement de santé
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Texas Cardiac Arrhythmia pays non établi dans la noticeÉtablissement de santé
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Brigham and Women's Hospital pays non établi dans la noticeÉtablissement de santé
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Harvard University pays non établi dans la noticeUniversité ou école supérieure
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Scripps Clinic pays non établi dans la noticeÉtablissement de santé
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MetroHealth Medical Center pays non établi dans la noticeÉtablissement de santé
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Case Western Reserve University Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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University of Modena and Reggio Emilia Department of Biomedical pays non établi dans la noticeUniversité ou école supérieure
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Azienda Ospedaliero-Universitaria di Modena pays non établi dans la noticeÉtablissement de santé
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Department of Cardio‐Thoraco‐Vascular Sciences and Public Health University of Padova Italy pays non établi dans la noticeUniversité ou école supérieure
University of Padua, University of Ferrara et St David's Medical Center, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.