Cover Picture: Gingival mesenchymal stem cells derived from patients with rheumatoid arthritis treat experimental arthritis (View 6/2024)

Résumé fourni par la source

In article number 20240021, the authors demonstrate that GMSC derived from patients with Rheumatoid Arthritis shared a similar expression of Immunophenotype with that from health donors. Survived for at least 24 days in a CIA mouse model following injection, RA GMSC reduced the joint histopathological scores of lymphocytes, osteoclasts, and cartilages. RA-GMSCs were also effective in suppressing inflamed synoviocyte in a humanized synovitis model as health GMSC does. As a new Elixir from RA patients, autologous GMSCs may have a promising therapeutic potential in patients with RA.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.