Pyoderma gangrenosum complicated by cerebral abscesses in an HIV-infected patient
Rattachement africain : Guinée. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Pyoderma gangrenosum (PG) is a rare ulcerative neutrophilic disease that usually affects the skin, with rare extracutaneous involvement. A few cases associated with HIV have been reported. We report a case with cerebral manifestations in the form of an abscess. A 35-year-old woman presented with a chronic ulceration of the left thigh that had been evolving for 6 months. The onset was progressive, marked by a pustule that became ulcerated, extending centrifugally and painfully. She had had multiple consultations with no improvement. Examination revealed an ulcero-necrotic lesion 6cm in diameter, with an infiltrated edge that was painful to palpate. Elsewhere, there were no particularities. Anatomopathological examination confirmed PG, serology tests were positive for HIV1, T-CD4 count was at 283 cells/mm3, and the viral load at 299 copies/ml. The patient was started on prednisone 1mg/kg/day and antiretrovirals, with good improvement after 3 weeks. Headache and left focal signs followed. Aetiologies of an intracranial expansive process were sought but were negative, and CT showed cerebral abscesses. The patient died five days later. In the case of PG, it is important to look for associated pathologies, particularly in the brain. Received: April 29th, 2024 Accepted: August 16th, 2024 https://dx.doi.org/10.4314/aamed.v17i4.17
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Pyoderma gangrenosum complicated by cerebral abscesses in an HIV-infected patient
- Date Crossref
- 29/10/2024
- Éditeur
- African Journals Online (AJOL)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Gamal Abdel Nasser University of Conakry Gamal Abdel Nasser University of Conakry, Guinée (code pays fourni par la source)Université ou école supérieure
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Donka Hospital Guinée (code pays fourni par la source)Établissement de santé
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Guinée / Faculté des Sciences et Techniques de la Santé Hôpital National Donka Conakry, Guinée (pays nommé en fin d’affiliation)Université ou école supérieure
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Hôpital National Donka Conakry, Guinée (pays nommé en fin d’affiliation)Établissement de santé
Gamal Abdel Nasser University of Conakry (Gamal Abdel Nasser University of Conakry, Guinée), Donka Hospital (Guinée) et Hôpital National Donka — Guinée / Faculté des Sciences et Techniques de la Santé (Conakry, Guinée), avec 1 autre affiliation. Pays d’affiliation : Guinée.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.