Correction: Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa

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Figs 3, 4 and 5 are uploaded incorrectly.Please see the correct Figs and associated captions here.Fig 3. Transmission-blocking effects of compounds when directly added to Plasmodium falciparum gametocyte field isolates prior to feeding.Effects of Atovaquone, DHA, Pyronaridine, Methylene blue, MMV390048, Ferroquine, DDD107498, P218 and Lumefantrine on the proportion of mosquitoes that became infected after feeding on gametocytes from naturally infected gametocyte donors where serum was replaced and the compound was added to the blood meal immediately prior to feeding.Every symbol represents an individual gametocyte donor whose blood was offered to mosquitoes with DMSO control (0.1% DMSO) or the compound at a single concentration.Lines connect experiments performed on the same blood aliquot; bars indicate the mean infection prevalence.The asterisks indicate statistical significance (p<0.05) in a Wilcoxon matched-pairs signed-rank test.Of note, the number of observations is small so lack of statistical significance should not be interpreted as evidence of no difference.Experiments with no infected mosquitoes in the DMSO control were not included in the statistical analyses.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.