The Evolution of African Swine Fever: Past, Present, and Future Perspectives

Résumé fourni par la source

African swine fever (ASF) poses a major threat to global swine health, impacting agriculture and food security worldwide. This chapter reviews the historical context, current challenges, and future prospects of the disease. It highlights the significant economic losses caused by ASF outbreaks and emphasizes the need for strict biosecurity measures, culling policies, and trade restrictions. The epidemiology of ASF is discussed in detail, covering its transmission cycles involving domestic pigs, wild suids, and soft ticks of the genus Ornithodoros. The African swine fever virus (ASFV) utilizes complex mechanisms to evade the immune system, complicating vaccine development. The chapter also reviews current diagnostic techniques, from traditional to advanced molecular and serological methods, stressing the importance of rapid and accurate detection. The immune response to ASFV is explored, focusing on innate and adaptive immunity, which is a key to developing effective vaccines. Various vaccine strategies are discussed, particularly live attenuated vaccines (LAVs), their potential, and associated safety concerns. The chapter concludes by emphasizing the need for continued research, innovation, and international collaboration to mitigate the impact of ASF on the swine industry. It aims to enhance understanding of ASF and inform strategies for its control and prevention.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.