Trajectories of abdominal subcutaneous and visceral adipose tissue accumulation and cardiometabolic health in children: The GUSTO study

Le résumé fourni par la source

Motivation: Unravel the links between childhood abdominal fat distribution patterns and subsequent cardiometabolic risks aiming to provide effective strategies for preventing childhood obesity. Goal(s): To investigate the presence of distinct abdominal fat accumulation patterns during infancy and childhood in a multi-ethnic cohort, and their associations with cardiometabolic risk. Approach: Latent class growth mixture modeling was used to identify three trajectories (stable, slow acceleration, rapid acceleration) for deep subcutaneous (DSAT), superficial subcutaneous (SSAT), and visceral adipose tissues (VAT). Results: Compared to Chinese children, Indian children had higher odds of being in the rapid acceleration trajectory. All accelerated trajectories were associated with inflammatory marker, hsCRP. Impact: This research has the potential to impact public health by providing evidence-based insights into the relationships between abdominal fat distribution patterns and cardiometabolic health. Our findings may aid development of targeted interventions and strategies to mitigate long-term adverse cardiometabolic consequences.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.