7 Tesla MRI in routine surgical planning for Deep Brain Stimulation for Parkinson’s Disease

Le résumé fourni par la source

Motivation: Identifying the dorsolateral subthalamic nucleus (STN) for deep brain stimulation (DBS) in Parkinson’s disease (PD) can be challenging due to the size and double-oblique orientation. Goal(s): To evaluate the influence of 7T T2w-TSE and probabilistic tractography on STN target planning, micro-electrode recordings and motor improvement. Approach: We describe the implementation of 7T T2w-TSE and probabilistic tractography in 182 PD patients undergoing STN DBS at our centre from 2015-2022. Results: Implementation of 7T T2w-TSE for STN DBS enabled a refinement in targeting which can be used as basis for adding probabilistic subthalamic connectivity, in order to enhance clinical outcome of STN DBS. Impact: The extensive evaluation of 360 STNs has not been described previously and shows 7T T2w-TSE and probabilistic tractography can refine STN targeting and surgical efficiency in DBS for PD.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.