Assessing the Impact of Vitamin D Supplementation on Respiratory Infections in Children and Adolescents: A Cross-Sectional Study
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Le résumé fourni par la source
Background and Objectives: Recent studies suggest that vitamin D supplementation and higher serum 25-hydroxyvitamin D (25-OHD) concentrations may reduce the incidence of respiratory infections in children and adolescents. This cross-sectional study aimed to evaluate the association between different concentrations of vitamin D supplementation, serum 25-OHD concentrations, and the frequency of respiratory infections among individuals aged 1 to 18 years, for a duration of 2 years. Methods: Concerning sun exposure in relation to vitamin D, the study took place in Romania, at approximately 45-degree northern latitude. A total of 194 patients were divided into groups based on weekly vitamin D supplementation (<400 IU, 400–800 IU, >800 IU), serum 25-OHD concentrations (<20 ng/mL, 20–30 ng/mL, >30 ng/mL), and age (<6 years, 6–12 years, 12–18 years). The overall incidence of respiratory infections was 41.2%. Results: Participants receiving >800 IU/week had a significantly lower incidence of infections (16.7%) compared to those receiving <400 IU/week (60.0%, p < 0.001). Similarly, participants with serum 25-OHD concentrations >30 ng/mL had an infection rate of 16.7%, compared to 61.4% in those with concentrations <20 ng/mL (p < 0.001). Age-specific analyses revealed that the protective effect of vitamin D was most pronounced in children under 6 years old. Logistic regression showed that higher vitamin D supplementation and serum 25-OHD concentrations were independently associated with reduced odds of respiratory infections (OR = 0.25 and OR = 0.22, respectively, p < 0.001). Conclusions: These findings support the potential role of vitamin D supplementation in preventing respiratory infections in the pediatric population.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Assessing the Impact of Vitamin D Supplementation on Respiratory Infections in Children and Adolescents: A Cross-Sectional Study
- Date Crossref
- 19/11/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Victor Babeș University of Medicine and Pharmacy Timișoara Department V of Internal Medicine I and Medical Semiology II pays non établi dans la noticeUniversité ou école supérieure
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“Victor Babes” University of Medicine and Pharmacy Timisoara Doctoral School pays non établi dans la noticeUniversité ou école supérieure
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"Victor Babes" University of Medicine and Pharmacy Timisoara Doctoral School pays non établi dans la noticeUniversité ou école supérieure
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Laboratory Medicine pays non établi dans la noticeStructure de recherche
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Faculty of Dentistry Department of Restorative Dentistry pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Dental Medicine Department of Pedodontics pays non établi dans la noticeUniversité ou école supérieure
Department V of Internal Medicine I and Medical Semiology II — Victor Babeș University of Medicine and Pharmacy Timișoara, Doctoral School — “Victor Babes” University of Medicine and Pharmacy Timisoara et Doctoral School — "Victor Babes" University of Medicine and Pharmacy Timisoara, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.