Association between Hematological Parameters and Severity of COVID-19 disease
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Le résumé fourni par la source
Background This study aimed to determine the relationships between hematological parameters- hemoglobin, Total Leucocyte Counts (TLC), platelet counts, Absolute Neutrophil Counts (ANC), Absolute Lymphocyte Counts (ALC), Neutrophil Lymphocyte Ratio (NLR), Systemic Immune Inflammatory Index (SII), Neutrophil Monocyte Ratio (NMR), Platelet Lymphocyte Ratio (PLR) and the severity of COVID-19 disease and their use in predicting severity of COVID-19 disease. Methods and Material This was a prospective, observational, single-center study of 573 symptomatic adult inpatients of COVID 19 admitted to our tertiary care center. Statistical analysis used The above-mentioned hematological parameter levels were noted and compared between the two categories of COVID-19 disease, namely non-severe and severe COVID-19 using logistic regression methods. Their cut-off values were detected using the ROC curve. Results The median TLC, ANC, NLR, SII, NMR, PLR were notably higher in patients with severe COVID-19 than in those with non-severe COVID-19. Logistic regression analysis showed that NMR (OR=1.029, p=0.006) and ALC (OR=0.999, p=0.002) were statistically significant independent predictors of COVID-19 severity. Conclusions The hematological parameters mentioned, can be used for predicting severe COVID-19 disease at admission. ALC and NMR levels could be used as hematological markers to predict severity of COVID-19 in adult patients with their cut off values being < 1105 cells/cubic millimeter and > 10.434 respectively.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Association between Hematological Parameters and Severity of COVID-19 disease
- Date Crossref
- 08/11/2024
- Éditeur
- F1000 Research Ltd
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Manipal Academy of Higher Education pays non établi dans la noticeUniversité ou école supérieure
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Kasturba Medical College Department of General Medicine pays non établi dans la noticeUniversité ou école supérieure
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K.S. Hegde Hospital pays non établi dans la noticeÉtablissement de santé
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Mangalore Institute of Oncology pays non établi dans la noticeÉtablissement de santé
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Voluntary Health Services Hospital General Medicine pays non établi dans la noticeÉtablissement de santé
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Institute of Medical Sciences Hematology and hematooncology pays non établi dans la noticeUniversité ou école supérieure
Manipal Academy of Higher Education, Department of General Medicine — Kasturba Medical College et K.S. Hegde Hospital, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.