Pharmacognostic Standardization and Chemical Study of Euphorbia nutans Lag. Euphorbiaceae
Rattachement africain : Nigéria, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Aims: This study was designed to set macro/micro morphological standards, phytochemical and physicochemical parameters for the identification of E. nutans, a traditional remedy for the management of many disesases. Study Design: To establish pharmacognostic standards for proper identification of E. nutans and also study its phytochemicals using Gas Chromatography coupled to Mass Spectrometry (GC-MS). Place and Duration: This work was undertaken at the Department of Pharmacognosy and Natural Medicine, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria for three month spanning from April through June, 2022. Methodology: Examination of microscopic characters, venation, chemomicroscopy, micromeritic properties, fluorescence analysis and phytochemical profiling using Gas Chromatography-Mass Spectrometry (GC-MS) were carried out. Results: Epidermal cell shapes were irregular with undulate-sinuous anticlinal walls. Stomatal distribution was amphistomatic with anisocytic and anomocytic stomata on both surfaces. Areolation was quadrangular, linear and biforked vein termination. The fluorescence characteristics showed the presence of different colours supporting the presence of various phytoconstituents for both leaf and stem. The flow properties for both leaf and stem were poor while GC-MS analysis of the dichloromethane extracts revealed lupeol (64.05%), 2-methylhexacosane (9.37%), stigmasterol (4.16%) and campesterol (1.29%) as major components in the leaf while campesterol (0.67%), stigmasterol (2.15 %), beta.-sitosterol (6.22%), lupeol (9.85%) and vitamin E (1.05%) for the stem extract. Conclusion: The results of the study could be useful for correct identification, standardization and preparation of monograph.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Pharmacognostic Standardization and Chemical Study of Euphorbia nutans Lag. Euphorbiaceae
- Date Crossref
- 04/11/2024
- Éditeur
- Sciencedomain International
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Uyo University of Uyo, Nigéria (code pays fourni par la source)Université ou école supérieure
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Niger Delta University Department of Pharmaceutical and Medicinal Chemistry Niger Delta University, Nigéria (code pays fourni par la source)Université ou école supérieure
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Madonna University Department of Clinical Pharmacy and Pharmacy Practice Rivers State, Nigéria (pays nommé en fin d’affiliation)Université ou école supérieure
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Madonna University Nigéria (code pays fourni par la source)Université ou école supérieure
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Faculty of Pharmacy Department of Pharmacognosy and Natural Medicine University of Uyo, Nigéria (pays nommé en fin d’affiliation)Université ou école supérieure
University of Uyo (University of Uyo, Nigéria), Department of Pharmaceutical and Medicinal Chemistry — Niger Delta University (Niger Delta University, Nigéria) et Department of Clinical Pharmacy and Pharmacy Practice — Madonna University (Rivers State, Nigéria), avec 2 autres affiliations. Pays d’affiliation : Nigéria.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.