A community-based peer-facilitated psychological and social support model to improve retention in care among Cameroonian adolescents perinatally infected with human immunodeficiency virus: A randomized controlled trial
Rattachement africain : Cameroun, Mali, fr, Éthiopie. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Psychological and social support for adolescents living with HIV remains undocumented and unaddressed in Central Africa. This study aimed at assessing effectiveness of a peer-facilitated community-based support model in improving retention in care among adolescents living with HIV and attending care in Chantal Biya Foundation, Yaounde, Cameroon. MATERIALS AND METHODS: We conducted an analysis of adolescents aged 10-19 years old, perinatally infected with HIV, on follow-up in the Day Care Unit of a reference hospital in Yaounde, Cameroon, and enrolled in the IAS-CIPHER-2021/1214-ATE-SMAVI, a individually randomized controlled trial. While the control arm only received routine care in the health facility, the intervention arm, in addition, was assigned to an HIV association for sustained support model, including support groups, leisure workshops and home visits. Structured questionnaires, including validated French versions of mental health scales, were quarterly administered to the study participants in both study arms by trained healthcare providers. The main outcome was maintaining retention in care beyond the first 15-month period of the study start. Kaplan-Meier and Cox regression models were fitted to assess association between intervention and outcome. Hazard Ratio (HR) across categories of exposure variables were compared using Wald's test. p-value <0.05 was considered significant. RESULTS: In total, 305 adolescents were recruited in the study at a median age of 15.2 years old, including 162 (53.1 %) females and 153 individuals in the intervention arm. Mental health troubles were prevalent: severe depression (26.9 %), high or very high anxiety (28.9 %), and low self-esteem (84.9 %). Noteworthy, all of the baseline characteristics were balanced irrelevant to the study arm. Probability of maintaining good retention in care beyond the first 15-month period of study start remained higher in the intervention arm (82.0 % [95 %CI: 73.7 %-88.4 %]) versus the control arm (71.0 % [95 %CI: 63.2 %-78.1 %]), [cHR (95 %CI): 2.0 (1.1-3.3), p=0.044]. CONCLUSIONS: Capacity should be built in terms of implementing community-based peer-facilitated support groups in local organizations providing care to adolescents living with HIV.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A community-based peer-facilitated psychological and social support model to improve retention in care among Cameroonian adolescents perinatally infected with human immunodeficiency virus: A randomized controlled trial
- Date Crossref
- 01/12/2024
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Ministry of Public Health Yaounde, Cameroun (code pays fourni par la source)Organisme public
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Université de Garoua Université de Garoua, Cameroun (code pays fourni par la source)Université ou école supérieure
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University of Douala University of Douala, Cameroun (code pays fourni par la source)Université ou école supérieure
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Centre Pasteur du Cameroun Yaounde, Cameroun (code pays fourni par la source)Structure de recherche
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Centre International De Reference Chantal Biya Cameroun (code pays fourni par la source)Institution
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University of Bamako University of Bamako, Mali (code pays fourni par la source)Université ou école supérieure
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Hôpital Robert-Debré pays non établi dans la noticeÉtablissement de santé
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Institute for Sustainable Development Abidjan, Éthiopie (code pays fourni par la source)Organisation à but non lucratif
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Institut de Recherche pour le Développement pays non établi dans la noticeOrganisme public
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Université de Yaoundé I Université de Yaoundé I, Cameroun (code pays fourni par la source)Université ou école supérieure
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Faculty of Medicine and Biomedical Sciences Cameroun Yaounde, Cameroun (pays nommé en fin d’affiliation)Université ou école supérieure
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Media Convergence Consulting Office Yaounde, Cameroun (pays nommé en fin d’affiliation)Institution
Ministry of Public Health (Yaounde, Cameroun), Université de Garoua (Université de Garoua, Cameroun) et University of Douala (University of Douala, Cameroun), avec 9 autres affiliations. Pays d’affiliation : Cameroun, Mali, Éthiopie.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.