Collagens and Elastic Fiber Proteins in Lung Development

Résumé fourni par la source

The orderly deposition and remodeling of fibrous and elastic matrices and basement membranes is essential for the structural development of the conducting airways, pulmonary blood vessels, alveoli, and pleura. In addition to their important structural roles, matrix macromolecules participate in regulating critical aspects of pulmonary morphogenesis, including airway branching and epithelial differentiation. Although the number of matrix proteins that contribute to lung structure is quite large, this chapter focuses on two major classes of lung matrix macromolecules—the collagens and elastic fiber proteins—and examines their roles in human lung development.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.