Abstract P140: Social Determinants of Health and Biologic Measures Differ by Hypertension Treatment Status Between Participants in Two Similar Clinical Trials

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Background: A disproportionate number of Black adults do not receive hypertension (HTN) treatment. Identifying the social determinants of health (SDoH) and biologic measures related to HTN treatment among Black adults may inform clinical strategies that promote HTN control. Objective: To identify SDoH and physical measures associated with HTN treatment among participants of two community-based trials. We hypothesized that SDoH and biologic measures would be associated with HTN treatment. Methods: GoFresh (NCT05121337) and GoFreshRx (NCT05393232) are two randomized controlled trials with a shared recruitment drive, investigating the effectiveness of home-delivered DASH-patterned groceries on blood pressure among Black adults with untreated and treated HTN, respectively. HTN treatment was self-reported during prescreening. We examined the association of SDoH and biologic measures with HTN treatment, using logistic regression adjusted for age and sex. Results: All participants were Black with mean age 45.8 (SD 16.1) yr and 36.9% on stable HTN treatment. Age, having a primary care physician, higher depressive symptoms, higher body mass index, and higher triglycerides were associated with hypertension treatment, while home ownership and higher high density lipoprotein cholesterol were associated with lower odds of HTN treatment (Table). Other factors did not significantly differ among participants in the two trials (notably, household income, insurance status, education, and food insecurity). Conclusion: In this community sample of Black adults, multiple SDoH and biologic factors were associated with HTN treatment. Future research should examine whether interventions addressing these factors can improve treatment rates.

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