Association Between Serum Vitamin D Level and Common Vestibular Disorders- A Cross-Sectional Study in a Tertiary Care Hospital

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Background: Vestibular disorders are a common cause of disabling vertigo and low serum vitamin D can lead to labyrinthine demineralization, otoconial fragility and modulation of pro-inflammatory mediators.It can be hypothesized that there exists an association between low serum vitamin D levels and vestibular disorders.To determine the association between serum Vitamin D levels and common vestibular disorders.Methods: We conducted a cross-sectional study on 100 subjects of both sexes above 18 years of age in a tertiary care hospital over 3 months to measure vitamin D levels in patients with vestibular disorders.Patients presenting to the outpatient underwent clinical, audiological and vestibular examination and were diagnosed with BPPV, Meniere's disease, or vestibular neuritis.Serum Vitamin D levels were measured for all and compared.Results: Of the 100 patients studied, 54 were females and 46 were males, while the age range was 25-66 years.The mean serum vitamin D level for patients of BPPV, Meniere's, and vestibular neuritis was 14.5±5.9ng/ml, 16.9±6.7 ng/ml, and 21.6±7.5 ng/ml, respectively.The results showed that serum vitamin D levels were significantly low in patients with BPPV (p=0.006) and deficiency was also observed in Meniere's disease.Conclusion: This study concluded that patients of BPPV and Meniere's disease also suffer from Vitamin D deficiency.Measurement of vitamin D levels in patients with vestibular disorders like BPPV can be beneficial for further management and treatment.

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