Mpox in UK households: estimating secondary attack rates and factors associated with transmission, May–November 2022
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Le résumé fourni par la source
Abstract We aimed to estimate the secondary attack rate of mpox among UK household contacts and determine factors associated with transmission to inform public health management of contacts, during the global outbreak in 2022. Information was collected via NHS and public health services and included age, gender, place of residence, setting, and type of contact. Aggregate information was summarized for the UK. Record level data was combined for England, Wales and Northern Ireland, and multivariable logistic regression was used to determine factors associated with transmission. The secondary attack rate among UK household mpox contacts was 4% (60/1 526). Sexual contact with the index case was associated with a 11-fold increase in adjusted odds of becoming a case in England, Wales, and Northern Ireland (95% CI 5.5–22, p < 0.001). Household contacts outside of London had increased odds compared to London residents (adjusted OR 2.9, 95%CI 1.6–5.4, p < 0.001), while female contacts had reduced odds of becoming a case (aOR: 0.41, 95% CI: 0.15–0.95). We found a low overall secondary attack rate among household mpox contacts with strong evidence of increased transmission risk associated with sexual contact. This evidence will inform the risk assessment of contacts and support prioritization of those with close intimate contact for follow up.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Mpox in UK households: estimating secondary attack rates and factors associated with transmission, May–November 2022
- Date Crossref
- 01/01/2024
- Éditeur
- Cambridge University Press (CUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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UK Health Security Agency UK Field Epidemiology Training Programme (UKFETP) pays non établi dans la noticeOrganisme public
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Public Health Wales pays non établi dans la noticeÉtablissement de santé
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Glasgow Caledonian University pays non établi dans la noticeUniversité ou école supérieure
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Public Health Scotland pays non établi dans la noticeOrganisme public
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Public Health Agency pays non établi dans la noticeInstitution
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Communicable Disease Surveillance Centre pays non établi dans la noticeInstitution
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School of Health and Life Sciences pays non établi dans la noticeUniversité ou école supérieure
UK Field Epidemiology Training Programme (UKFETP) — UK Health Security Agency, Public Health Wales et Glasgow Caledonian University, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.