Prevalence of potentially inappropriate medications and prescription dynamics in elderly hospitalized patients in Spain
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Le résumé fourni par la source
PURPOSE: In recent years, the need for a more appropriate prescription of medications in the older population has emerged as a significant public health concern. In this study, we aimed to evaluate the prevalence of potentially inappropriate medications (PIM) in hospitalized adults aged ≥ 75. PATIENTS AND METHODS: This was a retrospective descriptive observational study of patients at 16 hospitals in Spain. The study population included inpatients aged ≥ 75 admitted during a 7-day period (May 10 to 16, 2021). Data were obtained from the pharmacy databases of the participating hospitals. The list of PIMs was based on the Beers, STOPP-START, EU-PIM and PRISCUS criteria. RESULTS: A total of 4,183 patients were included. PIMs were detected in 23.5% (N = 1,126) of the cohort. The prevalence rates at the participating hospitals ranged from 10% to 42.5%. The PIM/patient ratio was 1.2. The most common PIMs were midazolam, dexketoprofen, diazepam, and doxazosin, all of which (except for doxazosin) were more common in women. Benzodiazepines accounted for 70% of all PIMs. In 35% of cases, the PIMs were initiated before hospital admission. Of the 818 PIMs initiated during hospitalization, the two most common were benzodiazepines (49%) and anti-inflammatory drugs (25%). At discharge, only 4.9% of the PIMs initiated during the hospital stay were still prescribed. CONCLUSION: In this population of older hospitalized patients, the overall prevalence of PIMs was moderate. However, the prevalence rate at the participating hospitals was highly variable. In most cases, PIMs prescribed prior to hospitalization for chronic conditions were not withdrawn during the hospital stay. No significant increase in PIMs was observed from pre-admission to post-discharge. These findings underscore the need for multidisciplinary interventions to optimize the pharmaceutical treatment in older adults in the hospital setting to reduce the consequences of PIMs in patients.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Prevalence of potentially inappropriate medications and prescription dynamics in elderly hospitalized patients in Spain
- Date Crossref
- 30/09/2024
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Universitat Autònoma de Barcelona pays non établi dans la noticeUniversité ou école supérieure
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Hospital de Sant Pau pays non établi dans la noticeÉtablissement de santé
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Centro de Investigación Biomédica en Red pays non établi dans la noticeStructure de recherche
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Navarre Institute of Health Research pays non établi dans la noticeUniversité ou école supérieure
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Hospital General Universitario Gregorio Marañón Geriatric Department pays non établi dans la noticeÉtablissement de santé
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Instituto de Investigación Sanitaria Gregorio Marañón pays non établi dans la noticeStructure de recherche
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Hospital de Sant Joan Despí Moisès Broggi pays non établi dans la noticeÉtablissement de santé
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Vall d'Hebron Hospital Universitari Pharmacy Department pays non établi dans la noticeÉtablissement de santé
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BioCruces Health research Institute pays non établi dans la noticeOrganisation à but non lucratif
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Hospital de Cruces pays non établi dans la noticeÉtablissement de santé
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Hospital de Basurto pays non établi dans la noticeÉtablissement de santé
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Donostiako Unibertsitate Ospitalea pays non établi dans la noticeÉtablissement de santé
Universitat Autònoma de Barcelona, Hospital de Sant Pau et Centro de Investigación Biomédica en Red, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.