A Pregnancy and Postnatal RCT Among Women With Gestational Diabetes Mellitus and Overweight/Obesity: The PAIGE2 Study
Rattachement africain : gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Objective This study examined the influence of a pregnancy and postnatal multicomponent lifestyle intervention for women with gestational diabetes mellitus (GDM) and overweight/obesity from 6 weeks to 12 months postnatal. The primary outcome was weight at 12 months. Secondary outcomes included change in body mass index (BMI), waist circumference (WC) and fasting plasma glucose (FPG). Methods The study involved 235 pregnant women with GDM and BMI ≥ 25 kg/m2 during pregnancy. Intervention components included an educational session, activity tracker (Fitbit), monthly phone calls, weekly motivational text messages, 12-week voucher for a commercial weight management organization and anthropometric, biochemical, and clinical measurements taken at 6 weeks, 6 months, and 12 months postnatal. The control group received routine local maternity care. Results A mean weight change of −2.0 (SD 7.1) kg was observed in the intervention group compared with −0.6 (SD 8.0) kg in the control group, difference −1.4 (95% CI −4.4, 1.5) kg from 6 weeks to 12 months postnatal, but this was not statistically significant (P = .34). Neither were significant differences obtained for any secondary outcomes: BMI −0.6 (−1.6, 0.5) kg/m2, WC −1.0 (−5.1, 3.2) cm and FPG 0.07 (−0.15, 0.29) mmol/L. Conclusion This lifestyle intervention among women with overweight/obesity and GDM resulted in a statistically nonsignificant 1.4 kg greater weight loss compared with routine care at 12 months postnatal. Further research is needed to understand how the different components of this lifestyle intervention might be better applied to elicit more successful results.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A Pregnancy and Postnatal RCT Among Women With Gestational Diabetes Mellitus and Overweight/Obesity: The PAIGE2 Study
- Date Crossref
- 27/08/2024
- Éditeur
- The Endocrine Society
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Belfast Health and Social Care Trust pays non établi dans la noticeÉtablissement de santé
-
Ulster Hospital Diabetes & Endocrinology pays non établi dans la noticeÉtablissement de santé
-
South Eastern Health and Social Care Trust pays non établi dans la noticeOrganisation à but non lucratif
-
Northern Health and Social Care Trust pays non établi dans la noticeÉtablissement de santé
-
Antrim Area Hospital Endocrine and Diabetes pays non établi dans la noticeÉtablissement de santé
-
Queen's University Belfast pays non établi dans la noticeUniversité ou école supérieure
-
Regional Centre for Endocrinology and Diabetes pays non établi dans la noticeInstitution
-
School of Medicine Centre for Public Health pays non établi dans la noticeUniversité ou école supérieure
Belfast Health and Social Care Trust, Diabetes & Endocrinology — Ulster Hospital et South Eastern Health and Social Care Trust, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.