The impact of the sputnik v vaccine on antibody responses in the general population of Golestan province, Iran

Résumé fourni par la source

Background: Although public health interventions have slowed the spread of SARS-CoV-2 infections, the worldwide pandemic of COVID-19 is progressing.Thus, effective and safe vaccination against SARS-CoV-2 is an important tool for controlling the COVID-19 pandemic.Now in the early stages of COVID-19 vaccination, vaccinated individuals are interested in using antibody tests to confirm vaccination success and estimate the time of protection.Here, we assessed anti-spike IgG responses in the general population 2 weeks after the second dose of the Sputnik V vaccine.Methods: This study included blood samples of 67 individuals without a previous SARS-CoV-2 infection taken 14 days after the second dose of the Sputnik V vaccine.Anti-spike IgG responses were assessed with an enzyme-linked immunosorbent assay (ELISA).Results: Anti-spike IgG was detected in 55 (82.1%) of 67 samples 14 days after the second dose of the Sputnik V vaccine.Antibody levels were significantly lower in males than in females, and 9 (75%) of 12 seronegative individuals were males.Conclusion: Vaccination resulted in detectable anti-spike IgG in 82.1% of individuals, and gender may be an important factor in the humoral response.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.