[Characteristic Analysis of Adult Acute Myeloid Leukemia Patients with PTPN11 Gene Mutation].

Le résumé fourni par la source

OBJECTIVE: gene mutation and its associated gene mutations in adult patients with acute myeloid leukemia (AML), and analyze its clinical characteristics. METHODS: Second-generation sequencing and Sanger sequencing were used to detect 51 gene mutations, and multiplex-PCR was used to detect 41 fusion genes from 451 newly diagnosed adult AML patients admitted to Affiliated Hospital of Jiangnan University, Changzhou Second People's Hospital, Wuxi People's Hospital and Wuxi Second People's Hospital from January 2017 to July 2022. RESULTS: (23.5%), etc . CONCLUSION: mutation is mostly manifested as M5 subtype, which is associated with higher platelet counts.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.