Cardiorespiratory Fitness Benefits of High-Intensity Interval Training After Stroke: A Randomized Controlled Trial
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Le résumé fourni par la source
BACKGROUND: Limited evidence supports the effects of short-interval high-intensity interval training (HIIT) for improving cardiorespiratory fitness (V̇O 2 peak) after stroke. We aimed to compare the effects of 12 weeks of short-interval HIIT versus moderate-intensity continuous training (MICT) on V̇O 2 peak, cardiovascular risk factors, and mobility outcomes among individuals ≥6 months poststroke. METHODS: This study was a multi-site, 12-week randomized controlled trial (NCT03614585) with an 8-week follow-up. Participants were randomized into 3 d/wk of HIIT (10×1 minute 80%–100% heart rate reserve interspersed with 1 minute 30% heart rate reserve [19 minutes]) or MICT (20–30 minutes 40%–60% heart rate reserve). Secondary outcomes of the trial, including V̇O 2 peak, cardiovascular risk factors (carotid-femoral pulse wave velocity, blood pressure, and waist-hip ratio), and mobility (6-minute walk test, 10 m gait speed), were reported. Linear mixed model analyses with a group×study time point interaction evaluated between-group differences. RESULTS: Of the 305 potential participants, 82 consented (mean [SD] age 64.9 [9.3] years, 32 females [39%], 1.8 [1.2] years poststroke) and were randomized to HIIT (n=42, mean [SD] baseline V̇O 2 peak 17.3 [5.9] mL/kg·min) or MICT (n=40, mean [SD] baseline V̇O 2 peak 17.2 [6.0] mL/kg·min). Participants attended 82% of visits (n=2417/2952). No adverse events occurred during the study period. A significant group×study time point interaction was found (χ 2 =8.46; P =0.015) for V̇O 2 peak at 12 weeks (mean difference, 1.81 [95% CI, 0.58–3.04]; P =0.004) whereby the HIIT group had greater gains in V̇O 2 peak (∆3.52 mL/kg·min [95% CI, 2.47–4.57]; P <0.001) compared with the MICT group (∆1.71 mL/kg·min [95% CI, 0.55–2.86]; P =0.001). There was no between-group difference in V̇O 2 peak (mean difference, 1.08 [95% CI, −0.26 to 2.42]; P =0.11) at 8-week follow-up. No group×study time point interactions were found for cardiovascular risk factors or mobility outcomes. CONCLUSIONS: Short-interval HIIT may be an effective alternative to MICT for improving V̇O 2 peak at 12 weeks postintervention. REGISTRATION: URL: https://clinicaltrials.gov ; Unique identifier: NCT03614585.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Cardiorespiratory Fitness Benefits of High-Intensity Interval Training After Stroke: A Randomized Controlled Trial
- Date Crossref
- 01/09/2024
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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McMaster University pays non établi dans la noticeUniversité ou école supérieure
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Jewish Rehabilitation Hospital pays non établi dans la noticeÉtablissement de santé
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McGill University Department of Kinesiology and Physical Education (S.N.S.) pays non établi dans la noticeUniversité ou école supérieure
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GF Strong Rehabilitation Centre pays non établi dans la noticeÉtablissement de santé
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Dalhousie University pays non établi dans la noticeUniversité ou école supérieure
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Jewish General Hospital pays non établi dans la noticeÉtablissement de santé
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School of Rehabilitation Sciences (K.M. pays non établi dans la noticeUniversité ou école supérieure
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Memory and Motor Rehabilitation Laboratory pays non établi dans la noticeStructure de recherche
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School of Physical and Occupational Therapy pays non établi dans la noticeUniversité ou école supérieure
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University of British Columba and Rehabilitation Research Program Department of Physical Therapy pays non établi dans la noticeUniversité ou école supérieure
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School of Physiotherapy pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Science Department of Health Research Methods Evidence and Impact (J.A.R.) pays non établi dans la noticeUniversité ou école supérieure
McMaster University, Jewish Rehabilitation Hospital et Department of Kinesiology and Physical Education (S.N.S.) — McGill University, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.