Epidemiological Features of Leptospirosis and Identification of Leptospira wolffii as a Persistently Prevailing Species in North–Central Bangladesh
Rattachement africain : bd, jp. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Leptospirosis is considered to be the most widespread, yet neglected, re-emerging zoonotic disease caused by infection with a pathogenic species of the genus Leptospira. Although this disease is prevalent in Bangladesh, the recent epidemiological status has not yet been well documented. In this study, we aimed to determine the prevalence of leptospirosis among febrile patients using different diagnostic methods and to characterize the epidemiological features and species of Leptospira in Mymensingh, north–central Bangladesh. Among the blood samples of 186 patients with suspected leptospirosis who met the inclusion criteria, including having a fever for more than 5 days (November 2021–June 2022), 88 samples (47%) were Leptospira-positive according to IgM LAT, IgM ELISA, or nested PCR (positivity rates: 38%, 37%, and 42%, respectively). Nested PCR showed a significantly higher positivity rate (54%) in patients with a short fever (5–10 day) than the other methods did, with lower rates among those with a longer fever. Leptospirosis cases were more common in males (68%), those 16–45 years of age (70%), residents of rural areas (81%), and farmers (41%). In addition to a fever, myalgia and jaundice were found in more than 70% of the patients, while variable symptoms were observed. The 16S rRNA sequencing analysis revealed that the Leptospira species in all the 22 samples tested were L. wolffii, belonging to the pathogenic subclade P2. This study showed the recent epidemiological features of leptospirosis in Bangladesh, indicating the presumptive predominance of L. wolffii since 2019.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Epidemiological Features of Leptospirosis and Identification of Leptospira wolffii as a Persistently Prevailing Species in North–Central Bangladesh
- Date Crossref
- 23/07/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Rangamati Science and Technology University pays non établi dans la noticeUniversité ou école supérieure
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Netrokona Medical College pays non établi dans la noticeUniversité ou école supérieure
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Mymensingh Medical College Hospital Department of Microbiology pays non établi dans la noticeÉtablissement de santé
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Pabna University of Science and Technology pays non établi dans la noticeUniversité ou école supérieure
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Sapporo Medical University pays non établi dans la noticeUniversité ou école supérieure
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Nilphamari Medical College Department of Microbiology pays non établi dans la noticeUniversité ou école supérieure
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Sirajganj 250 Bed Bongamata Sheikh Fazilatunnesa Mujib General Hospital Department of Ophthalmology pays non établi dans la noticeÉtablissement de santé
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Pabna Medical College Department of Microbiology pays non établi dans la noticeUniversité ou école supérieure
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School of Medicine Department of Hygiene pays non établi dans la noticeUniversité ou école supérieure
Rangamati Science and Technology University, Netrokona Medical College et Department of Microbiology — Mymensingh Medical College Hospital, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.