Abstract 1011: Evolving Burden Of Aortic Aneurysm Attributable To High Systolic Blood Pressure In 204 Countries And Territories From 1990-2019: A Comprehensive Global Assessment

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Introduction and Background: High blood pressure (HBP) is a major risk factor contributing to cardiovascular disease. Understanding the global burden of aortic aneurysms (AA) attributable to HBP is crucial for healthcare professionals, researchers, policymakers, and public health experts. Method: Using Global Burden of Disease tool, we estimated deaths, disability adjusted life years (DALYs) due to AA attributable to HBP by age, sex, year across the 204 countries and territories from 1990-2019. The results were employed in absolute counts and age-standardized rate (per 100,000 person years). Results: The study observed a notable increase in the total number of deaths due to AA attributable to HBP, rising from 36,629 in 1990 (95%[UI]: 28,841-44,353) to 59,880 in 2019 (46,691-72,639). Similarly, disability-adjusted life years (DALYs) escalated from 782,721 (629,321-944,867) in 1990 to 1,241,450 (1,015,874-1,468,103) in 2019. The most significant annual percentage change (APC) in the unadjusted death rate was recorded in the high-income Asia Pacific region, with an increase of 181%, followed by a 125% increase in the DALY rate in East Asia during the period from 1990-2019. In 2019, India, Japan, Russia, China, the United States, and Brazil accounted for 49.86% of the total global deaths. The highest mortality was seen in individuals aged 75-79 years, while the highest DALYs were observed in the 65-69 year age group. Over the past three decades, males have shown higher rates of death and disability compared to females. Conclusion: The study shows a marked global increase in both deaths and disability from AA attributable to HBP from 1990-2019, with significant regional disparities and a higher impact on older males, emphasizing the need for targeted healthcare strategies.

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