Effect of Curcuma longa Supplement on Cognitive Performance in Swiss Albino Mice
Rattachement africain : Nigéria. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Dementia is an age-related mental disorder and a characteristic symptom of various neurodegenerative disorders. Hyperglycemia affects areas of the brain crucial for learning and memory processes, potentially leading to cognitive impairments in individuals with diabetes. Curcuma longa (C. longa) contains many pharmacological and chemically important compounds with many beneficial effects. This study aimed to evaluate the effect of Curcuma longa on cognitive function in Swiss albino mice. A total of sixteen (16) mice of both sexes weighing between 24 – 30 grams were used for the study. The mice were divided into four groups of four mice each (N=4). Group I served as control and received 10 ml/kg distilled water; groups II, III and IV were given 5%, 10% and 20 % of Curcuma longa for 14 days respectively. Y maze and novel object recognition task were used to assess spatial working, long-term and recognition memories respectively. We observed that the 5% C. longa (77.60 ± 10.15%) group showed significant (p < 0.05) improvement in percentage alternation compared to the control group (64.40 ± 5.99%). We also found out that the 5% C. longa supplemented group showed a significant (p < 0.05) increase in both long-term memory (-14.08 ± 3.26) and discriminative index (-0.26 ± 0.07) when compared to control group (-31.55 ± 2.65) and (-0.33 ± 0.07) respectively. Thus, C. longa supplement at 5% improves spatial working memory, long-term memory and discriminative index of Swiss albino mice.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Effect of Curcuma longa Supplement on Cognitive Performance in Swiss Albino Mice
- Date Crossref
- 30/06/2024
- Éditeur
- IPS Intelligentsia Publishing Services
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Sa'adu Zungur University Nigéria (code pays fourni par la source)Université ou école supérieure
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Bayero University Kano Bayero University Kano, Nigéria (code pays fourni par la source)Université ou école supérieure
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Abubakar Tafawa Balewa University Department of Internal Medicine Bauchi, Nigéria (code pays fourni par la source)Université ou école supérieure
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Bauchi State University Gadau Department of Physiology Bauchi State University Gadau, Nigéria (ville ou établissement reconnu, pays non nommé)Université ou école supérieure
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Faculty of Basic Medical Sciences Department of Physiology Bauchi State University Gadau, Nigéria (pays nommé en fin d’affiliation)Université ou école supérieure
Sa'adu Zungur University (Nigéria), Bayero University Kano (Bayero University Kano, Nigéria) et Department of Internal Medicine — Abubakar Tafawa Balewa University (Bauchi, Nigéria), avec 2 autres affiliations. Pays d’affiliation : Nigéria.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.