Neuropsychological functioning after COVID-19: Minor differences between individuals with and without persistent complaints after SARS-CoV-2 infection
Rattachement africain : nl, gb, ca. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Objective: It is unclear how self-reported severe fatigue and difficulty concentrating after SARS-CoV-2 infection relate to objective neuropsychological functioning. The study aimed to compare neuropsychological functioning between individuals with and without these persistent subjective complaints. Method: Individuals with and without persistent severe fatigue (Checklist Individual Strength (CIS) fatigue ≥ 35) and difficulty concentrating (CIS concentration ≥ 18) at least 3 months after SARS-CoV-2 infection were included. Neuropsychological assessment was performed on overall cognitive functioning, attention, processing speed, executive functioning, memory, visuo-construction, and language (18 tests). T-scores −1.5 SD below population normative data (T ≤ 35) were classified as “impaired”. Results: 230 participants were included in the study, of whom 22 were excluded from the analysis due to invalid performance. Of the participants included in the analysis, 111 reported persistent complaints of severe fatigue and difficulty concentrating and 97 did not. Median age was 54 years, 59% (n = 126) were female, and participants were assessed a median of 23 months after first infection (IQR: 16–28). With bivariate logistic regression, individuals with persistent complaints had an increased likelihood of slower information processing speed performance on the Stroop word reading (OR = 2.45, 95%CI = 1.02–5.84) compared to those without persistent complaints. Demographic or clinical covariates (e.g. hospitalization) did not influence this association. With linear regression techniques, persistent complaints were associated with lower t-scores on the D2 CP, TMT B, and TMT B|A. There were no differences in performance on the other neuropsychological tests. Conclusions: Individuals with subjective severe fatigue and difficulty concentrating after COVID-19 do not typically demonstrate cognitive impairment on extensive neuropsychological testing.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Neuropsychological functioning after COVID-19: Minor differences between individuals with and without persistent complaints after SARS-CoV-2 infection
- Date Crossref
- 17/07/2024
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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GGD Amsterdam pays non établi dans la noticeÉtablissement de santé
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Amsterdam University Medical Centers pays non établi dans la noticeÉtablissement de santé
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University of Amsterdam Department of Medical Psychology pays non établi dans la noticeUniversité ou école supérieure
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Amsterdam Neuroscience pays non établi dans la noticeStructure de recherche
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GGZ inGeest pays non établi dans la noticeOrganisme public
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Vrije Universiteit Amsterdam Radiology & Nuclear Medicine pays non établi dans la noticeUniversité ou école supérieure
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University Medical Center Utrecht Department of Radiology and Nuclear Medicine pays non établi dans la noticeÉtablissement de santé
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MRC Cognition and Brain Sciences Unit pays non établi dans la noticeStructure de recherche
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Maastricht University School for Mental Health and Neuroscience pays non établi dans la noticeUniversité ou école supérieure
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VieCuri Medisch Centrum pays non établi dans la noticeÉtablissement de santé
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Leiden University pays non établi dans la noticeUniversité ou école supérieure
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Leiden University Medical Center pays non établi dans la noticeOrganisme public
GGD Amsterdam, Amsterdam University Medical Centers et Department of Medical Psychology — University of Amsterdam, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.