Clinical profile and investigations of acute kidney injury in neonates admitted to NICU.

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Background: Recent studies showed that critically ill neonates who were admitted to the neonate intensive care unit (NICU) may develop acute kidney injury (AKI) due to several risk factors thus resulting in a high mortality rate.Purpose: Diagnosis of acute kidney injury in neonates admitted to Neonatal Intensive Care Units.Patients and Methods: This was a case-control study. Conducted at the NICU, Faculty of Medicine Beni-Suef University Hospital from August 2020 to March 2021. The current study was conducted on 55 neonates (35 critically ill neonates and 20 healthy neonates admitted for phototherapy as a control group)Results: The gestational age didn't show significant differences between cases and controls. Body weight showed a significant decrease in neonates with sepsis in comparison with controls. The respiratory rate (RR) and systolic blood pressure (BP) were significantly elevated in cases compared to the control. Hemoglobin and platelets were significantly lower in cases than controls while white blood cells were significantly increased in cases compared to controls. Plasma creatinine level was significantly elevated in cases compared to controlsConclusion: 30% of neonates admitted to NICU developed AKI, especially with risk factors such as high RR, high systolic BP, anemia, and thrombocytopenia

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