Retinoblastoma: The Situation in Burkina Faso over Ten Years
Rattachement africain : Burkina Faso. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Context: In Burkina Faso, there is only one retinoblastoma treatment center located in the capital. Nowadays, the treatment of retinoblastoma has benefited from the contribution of scientific progress. Objective: The aim was to take stock of the situation of retinoblastoma in the pediatric oncology department from January 1, 2010 to December 31, 2019. Materials and Methods: This was a descriptive cross-sectional study with retrospective data collection over a 10-year period, based on records of patients admitted to pediatric oncology department of CHU-YO. Data were analysed using CS Pro version 7.2 software. Categorical variables were compared using Pearson’s Chi-square test at the 5% significance level. Overall survival was estimated using the Kaplan-Meier method. Operational definitions were used for lost to follow-up, consultation and diagnosis delays. Results: We collected a total of 204 cases in 10 years, i.e. an annual average of 20.4 cases/year. The mean age at diagnosis was 37.5 months for unilateral cases and 26.4 months for bilateral cases. Male predominance was noted, with a sex ratio of 1.31. The majority of patients came from disadvantaged backgrounds (72% farming fathers and 91% housewives). Clinically, leukocoria and exophthalmos were the main presenting features. The average time to consultation was long (8.73 months) and unilateral localization was predominantly unilateral at 77%. In terms of treatment, 102 patients were eligible for curative treatment and 80 for palliative treatment. The prognosis was poor, with 41% death and numerous cases of lost to follow-up (18%). Overall survival was estimated at 32%. The factor associated with the lethality of retiniblastoma was the extension of the tumor to other organs. Conclusion: Recognition of the early clinical signs of retinoblastoma can anticipate the occurrence of this cancer. Health professionals should be encouraged to perform the Buckner test every time they come into contact with children aged 0 to 5, and the public should be encouraged to examine their children’s eyes.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Retinoblastoma: The Situation in Burkina Faso over Ten Years
- Date Crossref
- 01/01/2024
- Éditeur
- Scientific Research Publishing, Inc.
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Centre de Recherche en Santé de Nouna Burkina Faso (code pays fourni par la source)Organisme public
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Université Joseph Ki-Zerbo Burkina Faso (code pays fourni par la source)Université ou école supérieure
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Centre Hospitalier Universitaire Yalgado Ouédraogo Burkina Faso (code pays fourni par la source)Établissement de santé
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Nazi Boni University Burkina Faso (code pays fourni par la source)Université ou école supérieure
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West African Health Organisation Burkina Faso (code pays fourni par la source)Organisme public
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Regional University Hospital of Ouahigouya Ophthalmology Department Ouahigouya, Burkina Faso (pays nommé en fin d’affiliation)Université ou école supérieure
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National Center for the Fight against Blindness Ouagadougou, Burkina Faso (pays nommé en fin d’affiliation)Institution
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Nouna District Hospital Burkina Faso (pays nommé en fin d’affiliation)Établissement de santé
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University Hospital of Bogodogo Ouagadougou, Burkina Faso (pays nommé en fin d’affiliation)Université ou école supérieure
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University Hospital of Yalgado Ouedraogo Ouagadougou, Burkina Faso (pays nommé en fin d’affiliation)Université ou école supérieure
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University Hospital of Sourô Sanou Bobo-Dioulasso, Burkina Faso (pays nommé en fin d’affiliation)Université ou école supérieure
Centre de Recherche en Santé de Nouna (Burkina Faso), Université Joseph Ki-Zerbo (Burkina Faso) et Centre Hospitalier Universitaire Yalgado Ouédraogo (Burkina Faso), avec 8 autres affiliations. Pays d’affiliation : Burkina Faso.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.