Analysis of the performance of the Modified Kyoto Classification Scoring Model in predicting current Helicobacter Pylori infection

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Aims Helicobacter Pylori-infected gastric mucosa shows distinct manifestations under upper gastrointestinal endoscopy. Chinese studies established a new scoring system based on the Kyoto classification score and proved its accuracy in diagnosing HP currect infection in the Chinese population. We aimed in this study to evaluate its performance in the Tunisian Population. Methods This is a retrospective study conducted in a Tunisian Hospital including all patients who underwent gastroscopy from January 2022 to September 2023. Atrophy, hypertrophy of the gastric fold, nodularity, diffuse redness, sticky mucus, spotty redness, , fundic gland polyp and regular arrangement of collecting venules (RAC) were recorded according to the Kyoto classification of gastritis and the modified score was caculated . The HP infection status of patients was determined by histological examination of gastric biopsies. Area under the curve (AUROC) of the modified score was calculated. Results We included 361 patients with a male-to-female sex ratio of 0.8. The mean age was 52 years [9-92]. Upper gastrointestinal endoscopy was indicated for epigastric pain (49.3%), dyspepsia (16.3%), iron-deficiency anemia (11.6%), vomiting (6.1%), bleeding (4.4%), vitamin B12 deficiency (2.5%), and other symptoms in 9.8% (dysphagia, abdominal pain, diarrhea, etc.). Helicobacter pylori (HP) infection was detected in 82.8% of cases.The total score of the modified scoring model ranged from –4 to 14 points. The AUROC was 0,784 and the cutoff value was 3 points. The sensitivity and specificity of the cutoff value were 80% and 80.6%, respectively. Conclusions In our population, the modified Kyoto Classification Scoring Model was performant in accurately judging HP status. Therefore, using it routinely has promising clinical application value. Publication History Article published online: 15 April 2024 © 2024. European Society of Gastrointestinal Endoscopy. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

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