CODA (part 5): nuclear coordinate generation | HuBMAP | JHU-TMC v2

Le résumé fourni par la source

In this section, generate nuclear coordinates on thehigh-resolution H&E images through color deconvolution and identificationof two-dimensional intensity minimums in the hematoxylin channels of the images(corresponding to the dark blue nuclei). This calculation is done on thehigh-resolution tiff images saved inside pth10x. Note on cell detection: It is important that the cellcoordinates are generated on unregistered images, as warping caused by theregisteration process can cause inaccuracies in nuclear detection performed onthe registered images. Instead, detect coordinates on the unregistered images,then apply the registration transformations to the cell coordinates todetermine their positions in registered space.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.