Comparative study of feto-maternal outcome during 1st and 2nd wave of COVID-19 in department of obstetrics and gynaecology at a tertiary health care centre, South Gujarat

Résumé fourni par la source

Background: Initial data of COVID 19 in pregnancy from first wave (till first half of 2020) were reassuring but since September 2020, picture changed showing pregnancy as a significant risk factor for severity of illness and adverse feto-maternal outcome.Objectives: The aim of this study is an attempt to compare and contrast the outcomes of two waves in pregnant women from western India.Methods: Data was collected from retrospective review of case papers and labour room case record forms of individual patients during 1 st and 2 nd wave and secondary data analysis was done.All the maternal and neonatal parameters were analysed using descriptive statistics -SPSS 23 software.Results: Out of total of 404 COVID-19 positive pregnant women, 141 (34.9%) were symptomatic.In 1st wave, 23.5% pregnant women were symptomatic compared to 70.3% in 2nd wave.There was no significant difference noted between mode of delivery (normal delivery v/s LSCS) in both waves.A statistically significant difference was noted in rates of preterm vaginal birth between two waves i.e. 1.2% in first and 8.8% in second wave (p-value: 0.002) and still-birth rate i.e.2.0% and 10.5% (p=0.008).In first wave, 16% patients were severe to critically ill and required advanced oxygen support as compared to 63.2% of the patients in second wave (p value < 0.001).Maternal mortality due to COVID-19 disease was 10.3% and 59% respectively.Conclusion: In second wave, the number of symptomatic pregnant women, maternal morbidity and mortality and adverse neonatal outcomes were significantly higher than in first wave.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.