PD53-08 INTRODUCING A NEW SMARTPHONE APPLIED SEMEN ANALYZER, SPERMCELL™: A CROSS-SECTIONAL VALIDATION STUDY WITH A COMPARATIVE ANALYSIS AND A MINI PATIENT QUESTIONNAIRE ON A LARGE SAMPLE COHORT

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You have accessJournal of UrologyInfertility: Basic Research & Pathophysiology (PD53)1 May 2024PD53-08 INTRODUCING A NEW SMARTPHONE APPLIED SEMEN ANALYZER, SPERMCELL™: A CROSS-SECTIONAL VALIDATION STUDY WITH A COMPARATIVE ANALYSIS AND A MINI PATIENT QUESTIONNAIRE ON A LARGE SAMPLE COHORT Murat Dincer, Omer R. Yazar, Aykut Colakerol, Gokhan Cil, Serhat Yentur, Engin Kandirali, Ahmet Yaser Muslumanoglu, Atilla Semercioz, and M. Zafer Temiz Murat DincerMurat Dincer , Omer R. YazarOmer R. Yazar , Aykut ColakerolAykut Colakerol , Gokhan CilGokhan Cil , Serhat YenturSerhat Yentur , Engin KandiraliEngin Kandirali , Ahmet Yaser MuslumanogluAhmet Yaser Muslumanoglu , Atilla SemerciozAtilla Semercioz , and M. Zafer TemizM. Zafer Temiz View All Author Informationhttps://doi.org/10.1097/01.JU.0001009456.01770.91.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Standard semen analysis methods may exhibit variability between observers and human error; therefore, additional methods are needed to overcome these handicaps. In this study, we aimed to present a new smartphone-applied semen analyzer, Sperm Cell™, investigate its diagnostic efficacy by comparing it with the standard analysis method, and determine the user-friendly nature of the SpermCell™. METHODS: A cross-sectional study was conducted on a large sample cohort, including 102 men. Three semen analyses were performed for each semen sample. The first was the standard manual method, whereas the others were smartphone-based analyses performed by technicians and patients. We compared major semen parameters between the three semen analyses. The user-friendly nature of the analyzer was also evaluated with a mini-questionnaire completed by the participants. RESULTS: The determined median sperm count, motile sperm count, and percentage of motile sperms, on standard manual semen analysis, were 50.00×106/ml (0-160×106/ml), 23.94×106/ml (0-108×106/ml) and 50.00% (0-73.00%), respectively. Median sperm count and motile sperm count were 50.52×106/ml (<1-150×106/ml) vs. 55.77×106/ml (<1-160×106/ml) and 23.34×106/ml (0-105×106/ml) vs 23.53×106/ml (0-104×106/ml) for SpermCell™-based semen analysis performed by technician and patients themselves, respectively. The percentage of motile sperms was 47.40% (0-67.00%) vs. 47.61% (0-80.20%), respectively. All the parameters were statistically similar between the three semen analysis methods (p>0.05 for each). SpermCell™ analysis results were correlated with the standard manual method with up to 0.85 correlation coefficients. Diagnostic sensitivity and specificity were up to 100% and 95.40%. The mini-questionnaire results revealed that the analyzer is useful. CONCLUSIONS: The novel smartphone-applied semen analyzer is a helpful tool with acceptable diagnostic accuracy in determining the major semen parameters. It can be used as an efficient at-home point-of-care testing method in the initial assessment of couples with infertility concerns. Source of Funding: This work supported financially by the Hillal Biotech. Bioeng. Inc., Izmir, Turkey for providing SpermCell™ equipment © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1141 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Murat Dincer More articles by this author Omer R. Yazar More articles by this author Aykut Colakerol More articles by this author Gokhan Cil More articles by this author Serhat Yentur More articles by this author Engin Kandirali More articles by this author Ahmet Yaser Muslumanoglu More articles by this author Atilla Semercioz More articles by this author M. Zafer Temiz More articles by this author Expand All Advertisement PDF downloadLoading ...

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