A literature review and expert consensus statement on diagnostics in suspected metal implant allergy
Rattachement africain : de, cz, ch, se, nl, dk. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Although rare, allergic reactions to metal implants represent a diagnostic challenge in view of missing guidelines. OBJECTIVES: To develop an European expert consensus on characteristics of metal allergy reactions and the utility of various diagnostic tools in suspected metal implant allergy. METHODS: A nominal group technique (NGT) was applied to develop consensus statements. Initially an online literature database was created on a secure server to enable a comprehensive information. Twenty-three statements were formulated on potential aspects of metal implant allergy with a focus on diagnostics and grouped into five domains. For the consensus development, the panel of 12 experts initially did refine and reformulate those statements that were ambiguous or had unclear wording. By face-to-face (9/12) or virtual participation (3/12), an anonymous online voting was performed. RESULTS: Consensus (≥80% of agreement) was reached in 20/23 statements. The panel agreed that implant allergy despite being rare should be considered in case of persistent unexplained symptoms. It was, however, recommended to allow adequate time for resolution of symptoms associated with healing and integration of an implant. Obtaining questionnaire-aided standardized medical history and standardized scoring of patient outcomes was also considered an important step by all experts There was broad consensus regarding the utility/performance of patch testing with additional late reading. It was recognized that the lymphocyte transformation test (LTT) has to many limitations to be generally recommended. Prior to orthopaedic implant, allergy screening of patients without a history of potential allergy to implant components was not recommended. CONCLUSIONS: Using an expert consensus process, statements concerning allergy diagnostics in suspected metal implant allergy were created. Areas of nonconsensus were identified, stressing uncertainty among the experts around topics such as preoperative testing in assumed allergy, histological correlate of periimplant allergy and in vitro testing, which underscores the need for further research.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A literature review and expert consensus statement on diagnostics in suspected metal implant allergy
- Date Crossref
- 12/04/2024
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
München Klinik pays non établi dans la noticeÉtablissement de santé
-
Charles University Department of Dermatovenereology pays non établi dans la noticeUniversité ou école supérieure
-
University Hospital Kralovske Vinohrady Department of Dermatology and Allergology pays non établi dans la noticeÉtablissement de santé
-
University of Rostock pays non établi dans la noticeUniversité ou école supérieure
-
University of Basel Department of Dermatology and Allergology pays non établi dans la noticeUniversité ou école supérieure
-
University Hospital of Basel pays non établi dans la noticeÉtablissement de santé
-
Lund University pays non établi dans la noticeUniversité ou école supérieure
-
Skåne University Hospital pays non établi dans la noticeÉtablissement de santé
-
Amsterdam UMC Location Vrije Universiteit Amsterdam pays non établi dans la noticeÉtablissement de santé
-
University of Copenhagen Department of Dermatology and Allergy pays non établi dans la noticeUniversité ou école supérieure
-
Gentofte Hospital pays non établi dans la noticeÉtablissement de santé
-
Trier University of Applied Sciences pays non établi dans la noticeUniversité ou école supérieure
München Klinik, Department of Dermatovenereology — Charles University et Department of Dermatology and Allergology — University Hospital Kralovske Vinohrady, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.