Aggregated variant data from whole-genome sequenced tinnitus patients (TIGER)

Le résumé fourni par la source

Aggregated variant data obtained from tinnitus patients from Sweden. Uploaded datasets are storage in annotated csv files. Annotation was performed using VEP (v106), including population frequencies for each variant from gnomAD, non-finnish Europeans from gnomAD, and swedish population from SweGen project. Pathogenicity scores from CADD are also annotated for each variant. Variants from genes found to be enriched in a gene burden analysis can be found in this aggregated dataset. agg.tiger.csv - TIGER cohort is composed by 97 swedish whole-genome sequenced constant tinnitus patients. agg.jaguar.csv - JAGUAR cohort is composed by 147 swedish whole-exome sequenced tinnitus patients . agg.sevtin.csv - SEVTIN cohort is a subcohort from TIGER, with 34 WGS patients seggregating severe tinnitus phenotype. agg.controls.csv - Controls is a swedish population cohort composed by 151 whole-exome sequenced swedish individuals.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.